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Items: 1 to 20 of 118


An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.

Cho JH, Boyman O, Kim HO, Hahm B, Rubinstein MP, Ramsey C, Kim DM, Surh CD, Sprent J.

J Exp Med. 2007 Aug 6;204(8):1787-801. Epub 2007 Jul 30.


GIMAP5 regulates mitochondrial integrity from a distinct subcellular compartment.

Keita M, Leblanc C, Andrews D, Ramanathan S.

Biochem Biophys Res Commun. 2007 Sep 21;361(2):481-6. Epub 2007 Jul 23.


IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8 T cells.

Sandau MM, Winstead CJ, Jameson SC.

J Immunol. 2007 Jul 1;179(1):120-5.


Human resting CD4+ T cells are constitutively inhibited by TGF beta under steady-state conditions.

Classen S, Zander T, Eggle D, Chemnitz JM, Brors B, B├╝chmann I, Popov A, Beyer M, Eils R, Debey S, Schultze JL.

J Immunol. 2007 Jun 1;178(11):6931-40.


MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo.

Fischer UB, Jacovetty EL, Medeiros RB, Goudy BD, Zell T, Swanson JB, Lorenz E, Shimizu Y, Miller MJ, Khoruts A, Ingulli E.

Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7181-6. Epub 2007 Apr 13.


New twists of T cell fate: control of T cell activation and tolerance by TGF-beta and NFAT.

Sundrud MS, Rao A.

Curr Opin Immunol. 2007 Jun;19(3):287-93. Epub 2007 Apr 12. Review.


Cytokines and T-cell homeostasis.

Boyman O, Purton JF, Surh CD, Sprent J.

Curr Opin Immunol. 2007 Jun;19(3):320-6. Epub 2007 Apr 12. Review.


Tob genes in development and homeostasis.

Jia S, Meng A.

Dev Dyn. 2007 Apr;236(4):913-21. Review.


Lymphopenia-induced proliferation of donor T cells reduces their capacity for causing acute graft-versus-host disease.

Maeda Y, Tawara I, Teshima T, Liu C, Hashimoto D, Matsuoka K, Tanimoto M, Reddy P.

Exp Hematol. 2007 Feb;35(2):274-86.


Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration.

Bracci L, Moschella F, Sestili P, La Sorsa V, Valentini M, Canini I, Baccarini S, Maccari S, Ramoni C, Belardelli F, Proietti E.

Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):644-53.


The lymphocyte guard-IANs: regulation of lymphocyte survival by IAN/GIMAP family proteins.

Nitta T, Takahama Y.

Trends Immunol. 2007 Feb;28(2):58-65. Epub 2006 Dec 28. Review.


Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse.

Chen BJ, Deoliveira D, Cui X, Le NT, Son J, Whitesides JF, Chao NJ.

Blood. 2007 Apr 1;109(7):3115-23.


A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance.

Li L, Iwamoto Y, Berezovskaya A, Boussiotis VA.

Nat Immunol. 2006 Nov;7(11):1157-65. Epub 2006 Oct 1.


Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection.

Brown IE, Blank C, Kline J, Kacha AK, Gajewski TF.

J Immunol. 2006 Oct 1;177(7):4521-9.


Degradation of Tob1 mediated by SCFSkp2-dependent ubiquitination.

Hiramatsu Y, Kitagawa K, Suzuki T, Uchida C, Hattori T, Kikuchi H, Oda T, Hatakeyama S, Nakayama KI, Yamamoto T, Konno H, Kitagawa M.

Cancer Res. 2006 Sep 1;66(17):8477-83.


Blockade of transforming growth factor-{beta} signaling in tumor-reactive CD8(+) T cells activates the antitumor immune response cycle.

Zhang Q, Yang XJ, Kundu SD, Pins M, Javonovic B, Meyer R, Kim SJ, Greenberg NM, Kuzel T, Meagher R, Guo Y, Lee C.

Mol Cancer Ther. 2006 Jul;5(7):1733-43.

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