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Items: 1 to 20 of 59

1.

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.

DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB.

Cell Metab. 2008 Jan;7(1):11-20. doi: 10.1016/j.cmet.2007.10.002. Review.

2.

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.

DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19345-50. Epub 2007 Nov 21.

3.

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

Yuneva M, Zamboni N, Oefner P, Sachidanandam R, Lazebnik Y.

J Cell Biol. 2007 Jul 2;178(1):93-105.

4.

p53: new roles in metabolism.

Bensaad K, Vousden KH.

Trends Cell Biol. 2007 Jun;17(6):286-91. Epub 2007 May 3. Review.

PMID:
17481900
5.

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.

Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB.

Genes Dev. 2007 May 1;21(9):1037-49. Epub 2007 Apr 16.

6.

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.

Wieman HL, Wofford JA, Rathmell JC.

Mol Biol Cell. 2007 Apr;18(4):1437-46. Epub 2007 Feb 14.

7.

Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.

Krockenberger M, Honig A, Rieger L, Coy JF, Sutterlin M, Kapp M, Horn E, Dietl J, Kammerer U.

Int J Gynecol Cancer. 2007 Jan-Feb;17(1):101-6.

PMID:
17291239
8.
9.

Cancer's molecular sweet tooth and the Warburg effect.

Kim JW, Dang CV.

Cancer Res. 2006 Sep 15;66(18):8927-30. Review.

10.

Estradiol stimulates the biosynthetic pathways of breast cancer cells: detection by metabolic flux analysis.

Forbes NS, Meadows AL, Clark DS, Blanch HW.

Metab Eng. 2006 Nov;8(6):639-52. Epub 2006 Jun 30.

PMID:
16904360
11.

TIGAR, a p53-inducible regulator of glycolysis and apoptosis.

Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, Gottlieb E, Vousden KH.

Cell. 2006 Jul 14;126(1):107-20.

12.

Increased lipogenesis in cancer cells: new players, novel targets.

Swinnen JV, Brusselmans K, Verhoeven G.

Curr Opin Clin Nutr Metab Care. 2006 Jul;9(4):358-65. Review.

PMID:
16778563
13.

p53 regulates mitochondrial respiration.

Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, Hurley PJ, Bunz F, Hwang PM.

Science. 2006 Jun 16;312(5780):1650-3. Epub 2006 May 25.

14.

Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival.

Chaj├Ęs V, Cambot M, Moreau K, Lenoir GM, Joulin V.

Cancer Res. 2006 May 15;66(10):5287-94.

15.

Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.

Langbein S, Zerilli M, Zur Hausen A, Staiger W, Rensch-Boschert K, Lukan N, Popa J, Ternullo MP, Steidler A, Weiss C, Grobholz R, Willeke F, Alken P, Stassi G, Schubert P, Coy JF.

Br J Cancer. 2006 Feb 27;94(4):578-85.

16.

Oncogenic PI3K and its role in cancer.

Samuels Y, Ericson K.

Curr Opin Oncol. 2006 Jan;18(1):77-82. Review.

PMID:
16357568
17.

ATP citrate lyase inhibition can suppress tumor cell growth.

Hatzivassiliou G, Zhao F, Bauer DE, Andreadis C, Shaw AN, Dhanak D, Hingorani SR, Tuveson DA, Thompson CB.

Cancer Cell. 2005 Oct;8(4):311-21.

18.

KGF induces lipogenic genes through a PI3K and JNK/SREBP-1 pathway in H292 cells.

Chang Y, Wang J, Lu X, Thewke DP, Mason RJ.

J Lipid Res. 2005 Dec;46(12):2624-35. Epub 2005 Sep 14.

19.
20.

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

Porstmann T, Griffiths B, Chung YL, Delpuech O, Griffiths JR, Downward J, Schulze A.

Oncogene. 2005 Sep 29;24(43):6465-81.

PMID:
16007182

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