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Items: 1 to 20 of 55

1.

Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions.

Ribes-Zamora A, Mihalek I, Lichtarge O, Bertuch AA.

Nat Struct Mol Biol. 2007 Apr;14(4):301-7. Epub 2007 Mar 11.

PMID:
17351632
2.

The lethality of Ku86 (XRCC5) loss-of-function mutations in human cells is independent of p53 (TP53).

Ghosh G, Li G, Myung K, Hendrickson EA.

Radiat Res. 2007 Jan;167(1):66-79.

PMID:
17214517
3.

The biology of Ku and its potential oncogenic role in cancer.

Gullo C, Au M, Feng G, Teoh G.

Biochim Biophys Acta. 2006 Apr;1765(2):223-34. Epub 2006 Jan 25. Review.

PMID:
16480833
4.

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly.

Buck D, Malivert L, de Chasseval R, Barraud A, Fondanèche MC, Sanal O, Plebani A, Stéphan JL, Hufnagel M, le Deist F, Fischer A, Durandy A, de Villartay JP, Revy P.

Cell. 2006 Jan 27;124(2):287-99.

5.

The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination.

Adachi N, So S, Iiizumi S, Nomura Y, Murai K, Yamakawa C, Miyagawa K, Koyama H.

DNA Cell Biol. 2006 Jan;25(1):19-24.

PMID:
16405397
6.

Mechanisms of eukaryotic DNA double strand break repair.

Cahill D, Connor B, Carney JP.

Front Biosci. 2006 May 1;11:1958-76. Review.

PMID:
16368571
7.

Heterozygous inactivation of human Ku70/Ku86 heterodimer does not affect cell growth, double-strand break repair, or genome integrity.

Uegaki K, Adachi N, So S, Iiizumi S, Koyama H.

DNA Repair (Amst). 2006 Mar 7;5(3):303-11. Epub 2005 Dec 1.

PMID:
16325483
8.

Shelterin: the protein complex that shapes and safeguards human telomeres.

de Lange T.

Genes Dev. 2005 Sep 15;19(18):2100-10. Review.

9.

Mechanism of DNA double-strand break repair by non-homologous end joining.

Hefferin ML, Tomkinson AE.

DNA Repair (Amst). 2005 Jun 8;4(6):639-48. Epub 2005 Jan 23. Review.

PMID:
15907771
10.

Role of human Ku86 in telomere length maintenance and telomere capping.

Jaco I, Muñoz P, Blasco MA.

Cancer Res. 2004 Oct 15;64(20):7271-8.

11.

The DNA-dependent protein kinase: the director at the end.

Meek K, Gupta S, Ramsden DA, Lees-Miller SP.

Immunol Rev. 2004 Aug;200:132-41. Review.

PMID:
15242401
12.

Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86.

Myung K, Ghosh G, Fattah FJ, Li G, Kim H, Dutia A, Pak E, Smith S, Hendrickson EA.

Mol Cell Biol. 2004 Jun;24(11):5050-9.

13.

Unraveling V(D)J recombination; insights into gene regulation.

Jung D, Alt FW.

Cell. 2004 Jan 23;116(2):299-311. Review.

14.

Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses.

Kohli M, Rago C, Lengauer C, Kinzler KW, Vogelstein B.

Nucleic Acids Res. 2004 Jan 2;32(1):e3.

15.

Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line.

Omori S, Takiguchi Y, Suda A, Sugimoto T, Miyazawa H, Takiguchi Y, Tanabe N, Tatsumi K, Kimura H, Pardington PE, Chen F, Chen DJ, Kuriyama T.

DNA Repair (Amst). 2002 Apr 29;1(4):299-310.

PMID:
12509248
16.

Connecting chromosomes, crisis, and cancer.

Maser RS, DePinho RA.

Science. 2002 Jul 26;297(5581):565-9. Review.

PMID:
12142527
17.
18.

Targeted inactivation of p53 in human cells does not result in aneuploidy.

Bunz F, Fauth C, Speicher MR, Dutriaux A, Sedivy JM, Kinzler KW, Vogelstein B, Lengauer C.

Cancer Res. 2002 Feb 15;62(4):1129-33.

19.

Ku86 is essential in human somatic cells.

Li G, Nelsen C, Hendrickson EA.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):832-7. Epub 2002 Jan 15.

20.

DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency.

O'Driscoll M, Cerosaletti KM, Girard PM, Dai Y, Stumm M, Kysela B, Hirsch B, Gennery A, Palmer SE, Seidel J, Gatti RA, Varon R, Oettinger MA, Neitzel H, Jeggo PA, Concannon P.

Mol Cell. 2001 Dec;8(6):1175-85.

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