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Items: 1 to 20 of 47


Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C.

Nat Immunol. 2006 Oct;7(10):1048-56. Epub 2006 Sep 3.


Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.

Scheller M, Huelsken J, Rosenbauer F, Taketo MM, Birchmeier W, Tenen DG, Leutz A.

Nat Immunol. 2006 Oct;7(10):1037-47. Epub 2006 Sep 3.


Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.

Luckey CJ, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, Mathis D.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3304-9. Epub 2006 Feb 21.


Wnt signaling: complexity at the surface.

Cadigan KM, Liu YI.

J Cell Sci. 2006 Feb 1;119(Pt 3):395-402. Review.


Poor outcome of adult acute lymphoblastic leukemia patients carrying the (1;19)(q23;p13) translocation.

Piccaluga PP, Malagola M, Rondoni M, Ottaviani E, Testoni N, Laterza C, Visani G, Pileri SA, Martinelli G, Baccarani M.

Leuk Lymphoma. 2006 Mar;47(3):469-72.


Microarray data analysis: from disarray to consolidation and consensus.

Allison DB, Cui X, Page GP, Sabripour M.

Nat Rev Genet. 2006 Jan;7(1):55-65. Review. Erratum in: Nat Rev Genet. 2006 May;7(5):406.


Hematopoietic stem cells do not engraft with absolute efficiencies.

Camargo FD, Chambers SM, Drew E, McNagny KM, Goodell MA.

Blood. 2006 Jan 15;107(2):501-7. Epub 2005 Oct 4.


Core transcriptional regulatory circuitry in human embryonic stem cells.

Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA.

Cell. 2005 Sep 23;122(6):947-56.


Differential expression of novel potential regulators in hematopoietic stem cells.

Forsberg EC, Prohaska SS, Katzman S, Heffner GC, Stuart JM, Weissman IL.

PLoS Genet. 2005 Sep;1(3):e28.


CD133-positive hematopoietic stem cell "stemness" genes contain many genes mutated or abnormally expressed in leukemia.

Toren A, Bielorai B, Jacob-Hirsch J, Fisher T, Kreiser D, Moran O, Zeligson S, Givol D, Yitzhaky A, Itskovitz-Eldor J, Kventsel I, Rosenthal E, Amariglio N, Rechavi G.

Stem Cells. 2005 Sep;23(8):1142-53.


Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells.

Lawrence HJ, Christensen J, Fong S, Hu YL, Weissman I, Sauvageau G, Humphries RK, Largman C.

Blood. 2005 Dec 1;106(12):3988-94. Epub 2005 Aug 9.


SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells.

Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ.

Cell. 2005 Jul 1;121(7):1109-21.


Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

Adolfsson J, Månsson R, Buza-Vidas N, Hultquist A, Liuba K, Jensen CT, Bryder D, Yang L, Borge OJ, Thoren LA, Anderson K, Sitnicka E, Sasaki Y, Sigvardsson M, Jacobsen SE.

Cell. 2005 Apr 22;121(2):295-306.


The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection.

Sun G, Liu X, Mercado P, Jenkinson SR, Kypriotou M, Feigenbaum L, Galéra P, Bosselut R.

Nat Immunol. 2005 Apr;6(4):373-81. Epub 2005 Mar 6.


A general survey of thymocyte differentiation by transcriptional analysis of knockout mouse models.

Puthier D, Joly F, Irla M, Saade M, Victorero G, Loriod B, Nguyen C.

J Immunol. 2004 Nov 15;173(10):6109-18.


Origins of lymphocyte developmental programs: transcription factor evidence.

Rothenberg EV, Pant R.

Semin Immunol. 2004 Aug;16(4):227-38. Review.


Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.

Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Hamaguchi I, Nomiyama K, Hosokawa K, Sakurada K, Nakagata N, Ikeda Y, Mak TW, Suda T.

Nature. 2004 Oct 21;431(7011):997-1002.


GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.

Ling KW, Ottersbach K, van Hamburg JP, Oziemlak A, Tsai FY, Orkin SH, Ploemacher R, Hendriks RW, Dzierzak E.

J Exp Med. 2004 Oct 4;200(7):871-82.


Molecular signatures of proliferation and quiescence in hematopoietic stem cells.

Venezia TA, Merchant AA, Ramos CA, Whitehouse NL, Young AS, Shaw CA, Goodell MA.

PLoS Biol. 2004 Oct;2(10):e301. Epub 2004 Sep 28.


Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.

Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T.

Cell. 2004 Jul 23;118(2):149-61.

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