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Induction of tolerance in CD8+ T cells to a transgenic autoantigen expressed in the liver does not require cross-presentation.

Morimoto J, Tan X, Teague RM, Ohlén C, Greenberg PD.

J Immunol. 2007 Jun 1;178(11):6849-60.


Patterns of somatic mutation in human cancer genomes.

Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR.

Nature. 2007 Mar 8;446(7132):153-8.


Humoral immunity, inflammation and cancer.

Tan TT, Coussens LM.

Curr Opin Immunol. 2007 Apr;19(2):209-16. Epub 2007 Feb 2. Review.


Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells.

Sheasley-O'Neill SL, Brinkman CC, Ferguson AR, Dispenza MC, Engelhard VH.

J Immunol. 2007 Feb 1;178(3):1512-22.


Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self.

Lee JW, Epardaud M, Sun J, Becker JE, Cheng AC, Yonekura AR, Heath JK, Turley SJ.

Nat Immunol. 2007 Feb;8(2):181-90. Epub 2006 Dec 31.


Immunosuppressive strategies that are mediated by tumor cells.

Rabinovich GA, Gabrilovich D, Sotomayor EM.

Annu Rev Immunol. 2007;25:267-96. Review.


Incomplete differentiation of antigen-specific CD8 T cells in tumor-draining lymph nodes.

Hargadon KM, Brinkman CC, Sheasley-O'neill SL, Nichols LA, Bullock TN, Engelhard VH.

J Immunol. 2006 Nov 1;177(9):6081-90.


Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

Byron SA, Horwitz KB, Richer JK, Lange CA, Zhang X, Yee D.

Br J Cancer. 2006 Nov 6;95(9):1220-8. Epub 2006 Oct 17.


Over-expression of genes and proteins of ubiquitin specific peptidases (USPs) and proteasome subunits (PSs) in breast cancer tissue observed by the methods of RFDD-PCR and proteomics.

Deng S, Zhou H, Xiong R, Lu Y, Yan D, Xing T, Dong L, Tang E, Yang H.

Breast Cancer Res Treat. 2007 Jul;104(1):21-30. Epub 2006 Sep 27.


Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy.

Zarling AL, Polefrone JM, Evans AM, Mikesh LM, Shabanowitz J, Lewis ST, Engelhard VH, Hunt DF.

Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14889-94. Epub 2006 Sep 25.


The consensus coding sequences of human breast and colorectal cancers.

Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7.


Preferential involvement of CX chemokine receptor 4 and CX chemokine ligand 12 in T-cell migration toward melanoma cells.

Zhang T, Somasundaram R, Berking C, Caputo L, Van Belle P, Elder D, Czerniecki B, Hotz S, Schuchter L, Spitz FR, Berencsi K, Rani P, Marincola F, Qiu R, Herlyn D.

Cancer Biol Ther. 2006 Oct;5(10):1304-12. Epub 2006 Oct 4.


Development of WT1 peptide cancer vaccine against hematopoietic malignancies and solid cancers.

Oka Y, Tsuboi A, Kawakami M, Elisseeva OA, Nakajima H, Udaka K, Kawase I, Oji Y, Sugiyama H.

Curr Med Chem. 2006;13(20):2345-52. Review.


The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells.

Sumimoto H, Imabayashi F, Iwata T, Kawakami Y.

J Exp Med. 2006 Jul 10;203(7):1651-6. Epub 2006 Jun 26.


Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).

Grunda JM, Nabors LB, Palmer CA, Chhieng DC, Steg A, Mikkelsen T, Diasio RB, Zhang K, Allison D, Grizzle WE, Wang W, Gillespie GY, Johnson MR.

J Neurooncol. 2006 Dec;80(3):261-74. Epub 2006 Jun 14.


c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation.

Chen SY, Cai C, Fisher CJ, Zheng Z, Omwancha J, Hsieh CL, Shemshedini L.

Oncogene. 2006 Nov 16;25(54):7212-23. Epub 2006 May 29.


Immunity to melanoma antigens: from self-tolerance to immunotherapy.

Slingluff CL Jr, Chianese-Bullock KA, Bullock TN, Grosh WW, Mullins DW, Nichols L, Olson W, Petroni G, Smolkin M, Engelhard VH.

Adv Immunol. 2006;90:243-95. Review.


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