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Items: 1 to 20 of 59

2.

LKB1 modulates lung cancer differentiation and metastasis.

Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D, Chen L, Krishnamurthy J, Koivunen J, Chirieac LR, Padera RF, Bronson RT, Lindeman NI, Christiani DC, Lin X, Shapiro GI, Jänne PA, Johnson BE, Meyerson M, Kwiatkowski DJ, Castrillon DH, Bardeesy N, Sharpless NE, Wong KK.

Nature. 2007 Aug 16;448(7155):807-10. Epub 2007 Aug 5.

PMID:
17676035
3.

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics.

Szabó C, Ischiropoulos H, Radi R.

Nat Rev Drug Discov. 2007 Aug;6(8):662-80. Review.

PMID:
17667957
4.

Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing.

Garin G, Abe J, Mohan A, Lu W, Yan C, Newby AC, Rhaman A, Berk BC.

Circ Res. 2007 Jul 6;101(1):97-105. Epub 2007 May 24.

5.

LKB1/STRAD promotes axon initiation during neuronal polarization.

Shelly M, Cancedda L, Heilshorn S, Sumbre G, Poo MM.

Cell. 2007 May 4;129(3):565-77.

6.

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.

Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F.

Cell. 2007 May 4;129(3):549-63.

7.

Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance.

Herschkovitz A, Liu YF, Ilan E, Ronen D, Boura-Halfon S, Zick Y.

J Biol Chem. 2007 Jun 22;282(25):18018-27. Epub 2007 Apr 19. Retraction in: J Biol Chem. 2018 May 11;293(19):7266.

9.

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains.

Fox TE, Houck KL, O'Neill SM, Nagarajan M, Stover TC, Pomianowski PT, Unal O, Yun JK, Naides SJ, Kester M.

J Biol Chem. 2007 Apr 27;282(17):12450-7. Epub 2007 Feb 17.

10.

Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential.

Zhuang ZG, Di GH, Shen ZZ, Ding J, Shao ZM.

Mol Cancer Res. 2006 Nov;4(11):843-9.

11.

Peroxynitrite and myocardial contractility: in vivo versus in vitro effects.

Katori T, Donzelli S, Tocchetti CG, Miranda KM, Cormaci G, Thomas DD, Ketner EA, Lee MJ, Mancardi D, Wink DA, Kass DA, Paolocci N.

Free Radic Biol Med. 2006 Nov 15;41(10):1606-18. Epub 2006 Sep 5.

PMID:
17045928
12.

Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite.

Xu J, Xie Z, Reece R, Pimental D, Zou MH.

Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2688-95. Epub 2006 Oct 5.

13.

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3.

Koh HJ, Arnolds DE, Fujii N, Tran TT, Rogers MJ, Jessen N, Li Y, Liew CW, Ho RC, Hirshman MF, Kulkarni RN, Kahn CR, Goodyear LJ.

Mol Cell Biol. 2006 Nov;26(22):8217-27. Epub 2006 Sep 11.

14.

Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.

LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M.

J Biol Chem. 2006 Aug 25;281(34):24124-37. Epub 2006 Jun 23.

15.

LKB1-dependent signaling pathways.

Alessi DR, Sakamoto K, Bayascas JR.

Annu Rev Biochem. 2006;75:137-63. Review.

PMID:
16756488
16.

Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells.

Liu LZ, Zhao HL, Zuo J, Ho SK, Chan JC, Meng Y, Fang FD, Tong PC.

Mol Biol Cell. 2006 May;17(5):2322-30. Epub 2006 Mar 8.

17.

Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells.

Shacka JJ, Sahawneh MA, Gonzalez JD, Ye YZ, D'Alessandro TL, Estévez AG.

Cell Death Differ. 2006 Sep;13(9):1506-14. Epub 2006 Jan 20.

18.

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

Xie Z, Dong Y, Zhang M, Cui MZ, Cohen RA, Riek U, Neumann D, Schlattner U, Zou MH.

J Biol Chem. 2006 Mar 10;281(10):6366-75. Epub 2006 Jan 9.

19.

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.

Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC.

Science. 2005 Dec 9;310(5754):1642-6. Epub 2005 Nov 24.

20.

Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis.

Dickhout JG, Hossain GS, Pozza LM, Zhou J, Lhoták S, Austin RC.

Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2623-9. Epub 2005 Oct 6.

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