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Combination of VEGF(165)/Angiopoietin-1 gene and endothelial progenitor cells for therapeutic neovascularization.

Chen F, Tan Z, Dong CY, Li X, Xie Y, Wu Y, Chen X, Guo S.

Eur J Pharmacol. 2007 Jul 30;568(1-3):222-30. Epub 2007 May 10.


Synergistically therapeutic effects of VEGF165 and angiopoietin-1 on ischemic rat myocardium.

Liu X, Chen Y, Zhang F, Chen L, Ha T, Gao X, Li C.

Scand Cardiovasc J. 2007 Apr;41(2):95-101.


Improved angiogenic response in pig heart following ischaemic injury using human skeletal myoblast simultaneously expressing VEGF165 and angiopoietin-1.

Ye L, Haider HKh, Jiang S, Tan RS, Ge R, Law PK, Sim EK.

Eur J Heart Fail. 2007 Jan;9(1):15-22. Epub 2006 Jul 7.


AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect.

Su H, Huang Y, Takagawa J, Barcena A, Arakawa-Hoyt J, Ye J, Grossman W, Kan YW.

Gene Ther. 2006 Nov;13(21):1495-502. Epub 2006 Jun 15.


NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study.

Gyöngyösi M, Khorsand A, Zamini S, Sperker W, Strehblow C, Kastrup J, Jorgensen E, Hesse B, Tägil K, Bøtker HE, Ruzyllo W, Teresiñska A, Dudek D, Hubalewska A, Rück A, Nielsen SS, Graf S, Mundigler G, Novak J, Sochor H, Maurer G, Glogar D, Sylven C.

Circulation. 2005 Aug 30;112(9 Suppl):I157-65.


Angiopoietin 1 is mitogenic for cultured endothelial cells.

Kanda S, Miyata Y, Mochizuki Y, Matsuyama T, Kanetake H.

Cancer Res. 2005 Aug 1;65(15):6820-7.


Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow.

Cho CH, Kim KE, Byun J, Jang HS, Kim DK, Baluk P, Baffert F, Lee GM, Mochizuki N, Kim J, Jeon BH, McDonald DM, Koh GY.

Circ Res. 2005 Jul 8;97(1):86-94. Epub 2005 Jun 16. Erratum in: Circ Res. 2006 May 12;98(9):e69.


Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts.

Su H, Joho S, Huang Y, Barcena A, Arakawa-Hoyt J, Grossman W, Kan YW.

Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16280-5. Epub 2004 Nov 8.


VEGF165 and angiopoietin-1 decreased myocardium infarct size through phosphatidylinositol-3 kinase and Bcl-2 pathways.

Zhou L, Ma W, Yang Z, Zhang F, Lu L, Ding Z, Ding B, Ha T, Gao X, Li C.

Gene Ther. 2005 Feb;12(3):196-202. Erratum in: Gene Ther. 2005 Mar;12(6):552.


Pre-administration of angiopoietin-1 followed by VEGF induces functional and mature vascular formation in a rabbit ischemic model.

Yamauchi A, Ito Y, Morikawa M, Kobune M, Huang J, Sasaki K, Takahashi K, Nakamura K, Dehari H, Niitsu Y, Abe T, Hamada H.

J Gene Med. 2003 Nov;5(11):994-1004.


New technique for measurement of left ventricular pressure in conscious mice.

Ishizaka S, Sievers RE, Zhu BQ, Rodrigo MC, Joho S, Foster E, Simpson PC, Grossman W.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1208-15. Epub 2003 Oct 16.


Combination of angiopoietin-1 and vascular endothelial growth factor gene therapy enhances arteriogenesis in the ischemic myocardium.

Siddiqui AJ, Blomberg P, Wärdell E, Hellgren I, Eskandarpour M, Islam KB, Sylvén C.

Biochem Biophys Res Commun. 2003 Oct 24;310(3):1002-9.


Direct comparison of efficiency and stability of gene transfer into the mammalian heart using adeno-associated virus versus adenovirus vectors.

Chu D, Sullivan CC, Weitzman MD, Du L, Wolf PL, Jamieson SW, Thistlethwaite PA.

J Thorac Cardiovasc Surg. 2003 Sep;126(3):671-9.


Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors.

Vassalli G, Büeler H, Dudler J, von Segesser LK, Kappenberger L.

Int J Cardiol. 2003 Aug;90(2-3):229-38.


Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

Arsic N, Zentilin L, Zacchigna S, Santoro D, Stanta G, Salvi A, Sinagra G, Giacca M.

Mol Ther. 2003 Apr;7(4):450-9.


Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy.

Dor Y, Djonov V, Abramovitch R, Itin A, Fishman GI, Carmeliet P, Goelman G, Keshet E.

EMBO J. 2002 Apr 15;21(8):1939-47.


Coadministration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization.

Chae JK, Kim I, Lim ST, Chung MJ, Kim WH, Kim HG, Ko JK, Koh GY.

Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2573-8.

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