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Items: 18

1.

Profiling essential genes in human mammary cells by multiplex RNAi screening.

Silva JM, Marran K, Parker JS, Silva J, Golding M, Schlabach MR, Elledge SJ, Hannon GJ, Chang K.

Science. 2008 Feb 1;319(5863):617-20. doi: 10.1126/science.1149185.

2.

The genomic landscapes of human breast and colorectal cancers.

Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein B.

Science. 2007 Nov 16;318(5853):1108-13. Epub 2007 Oct 11.

3.

Non-oncogene addiction and the stress phenotype of cancer cells.

Solimini NL, Luo J, Elledge SJ.

Cell. 2007 Sep 21;130(6):986-8.

4.

The ubiquitin-specific protease USP28 is required for MYC stability.

Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R, Bernards R, Moll R, Elledge SJ, Eilers M.

Nat Cell Biol. 2007 Jul;9(7):765-74. Epub 2007 Jun 10.

PMID:
17558397
5.

A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.

Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ.

Nat Cell Biol. 2007 May;9(5):556-64. Epub 2007 Apr 8.

PMID:
17417629
6.

The consensus coding sequences of human breast and colorectal cancers.

Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7.

7.

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase.

Jin H, Sperka T, Herrlich P, Morrison H.

Nature. 2006 Aug 3;442(7102):576-9.

PMID:
16885985
8.

A loss-of-function RNA interference screen for molecular targets in cancer.

Ngo VN, Davis RE, Lamy L, Yu X, Zhao H, Lenz G, Lam LT, Dave S, Yang L, Powell J, Staudt LM.

Nature. 2006 May 4;441(7089):106-10. Epub 2006 Mar 29.

PMID:
16572121
9.

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.

Brummelkamp TR, Fabius AW, Mullenders J, Madiredjo M, Velds A, Kerkhoven RM, Bernards R, Beijersbergen RL.

Nat Chem Biol. 2006 Apr;2(4):202-6. Epub 2006 Feb 13.

PMID:
16474381
10.

Second-generation shRNA libraries covering the mouse and human genomes.

Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ.

Nat Genet. 2005 Nov;37(11):1281-8. Epub 2005 Oct 2.

PMID:
16200065
11.

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.

Dickins RA, Hemann MT, Zilfou JT, Simpson DR, Ibarra I, Hannon GJ, Lowe SW.

Nat Genet. 2005 Nov;37(11):1289-95. Epub 2005 Oct 2. Erratum in: Nat Genet. 2006 Mar;38(3):389.

PMID:
16200064
12.

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

Kolfschoten IG, van Leeuwen B, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Voorhoeve PM, Agami R.

Cell. 2005 Jun 17;121(6):849-58.

13.

A genetic screen for candidate tumor suppressors identifies REST.

Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ.

Cell. 2005 Jun 17;121(6):837-48.

14.

Myosin phosphatase: structure, regulation and function.

Ito M, Nakano T, Erdodi F, Hartshorne DJ.

Mol Cell Biochem. 2004 Apr;259(1-2):197-209. Review.

PMID:
15124925
15.

A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R.

Nature. 2004 Mar 25;428(6981):431-7.

PMID:
15042092
16.

A resource for large-scale RNA-interference-based screens in mammals.

Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, Aruleba S, Balija V, O'Shaughnessy A, Gnoj L, Scobie K, Chang K, Westbrook T, Cleary M, Sachidanandam R, McCombie WR, Elledge SJ, Hannon GJ.

Nature. 2004 Mar 25;428(6981):427-31.

PMID:
15042091
17.

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.

Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA.

Science. 2004 Feb 6;303(5659):844-8. Epub 2004 Jan 2.

18.

Normalization of cDNA microarray data.

Smyth GK, Speed T.

Methods. 2003 Dec;31(4):265-73.

PMID:
14597310

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