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Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities.

Guo K, McMinn JE, Ludwig T, Yu YH, Yang G, Chen L, Loh D, Li C, Chua S Jr, Zhang Y.

Endocrinology. 2007 Aug;148(8):3987-97. Epub 2007 May 10.


Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals.

Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL.

Nat Med. 2007 Jan;13(1):89-94. Epub 2006 Dec 31.


Leptin receptor signaling and action in the central nervous system.

Leshan RL, Björnholm M, Münzberg H, Myers MG Jr.

Obesity (Silver Spring). 2006 Aug;14 Suppl 5:208S-212S. Review.


Central nervous system control of food intake and body weight.

Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW.

Nature. 2006 Sep 21;443(7109):289-95. Review.


Leptin regulation of the mesoaccumbens dopamine pathway.

Fulton S, Pissios P, Manchon RP, Stiles L, Frank L, Pothos EN, Maratos-Flier E, Flier JS.

Neuron. 2006 Sep 21;51(6):811-22.


Leptin receptor signaling in midbrain dopamine neurons regulates feeding.

Hommel JD, Trinko R, Sears RM, Georgescu D, Liu ZW, Gao XB, Thurmon JJ, Marinelli M, DiLeone RJ.

Neuron. 2006 Sep 21;51(6):801-10.


Critical role of STAT3 in leptin's metabolic actions.

Buettner C, Pocai A, Muse ED, Etgen AM, Myers MG Jr, Rossetti L.

Cell Metab. 2006 Jul;4(1):49-60.


Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger ribonucleic acid.

Kaelin CB, Gong L, Xu AW, Yao F, Hockman K, Morton GJ, Schwartz MW, Barsh GS, MacKenzie RG.

Mol Endocrinol. 2006 Oct;20(10):2591-602. Epub 2006 May 18.


Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.

de Luca C, Kowalski TJ, Zhang Y, Elmquist JK, Lee C, Kilimann MW, Ludwig T, Liu SM, Chua SC Jr.

J Clin Invest. 2005 Dec;115(12):3484-93. Epub 2005 Nov 10.


Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis.

Bates SH, Kulkarni RN, Seifert M, Myers MG Jr.

Cell Metab. 2005 Mar;1(3):169-78.


Leptin receptor action and mechanisms of leptin resistance.

Münzberg H, Björnholm M, Bates SH, Myers MG Jr.

Cell Mol Life Sci. 2005 Mar;62(6):642-52. Review.


PI3K integrates the action of insulin and leptin on hypothalamic neurons.

Xu AW, Kaelin CB, Takeda K, Akira S, Schwartz MW, Barsh GS.

J Clin Invest. 2005 Apr;115(4):951-8. Epub 2005 Mar 10.


Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation.

Gao Q, Wolfgang MJ, Neschen S, Morino K, Horvath TL, Shulman GI, Fu XY.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4661-6. Epub 2004 Mar 22.


Essential role of STAT3 in body weight and glucose homeostasis.

Cui Y, Huang L, Elefteriou F, Yang G, Shelton JM, Giles JE, Oz OK, Pourbahrami T, Lu CY, Richardson JA, Karsenty G, Li C.

Mol Cell Biol. 2004 Jan;24(1):258-69.


STAT3 signalling is required for leptin regulation of energy balance but not reproduction.

Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E, Neel BG, Schwartz MW, Myers MG Jr.

Nature. 2003 Feb 20;421(6925):856-9.


Intracellular signalling. Key enzyme in leptin-induced anorexia.

Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers MG Jr, Schwartz MW.

Nature. 2001 Oct 25;413(6858):794-5. No abstract available.


Selective deletion of leptin receptor in neurons leads to obesity.

Cohen P, Zhao C, Cai X, Montez JM, Rohani SC, Feinstein P, Mombaerts P, Friedman JM.

J Clin Invest. 2001 Oct;108(8):1113-21.


Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex.

Graus-Porta D, Blaess S, Senften M, Littlewood-Evans A, Damsky C, Huang Z, Orban P, Klein R, Schittny JC, Müller U.

Neuron. 2001 Aug 16;31(3):367-79.


Effect of the genetic background on the reproduction of leptin-deficient obese mice.

Ewart-Toland A, Mounzih K, Qiu J, Chehab FF.

Endocrinology. 1999 Feb;140(2):732-8.


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