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Items: 1 to 20 of 62

1.

Gene-specific control of inflammation by TLR-induced chromatin modifications.

Foster SL, Hargreaves DC, Medzhitov R.

Nature. 2007 Jun 21;447(7147):972-8. Epub 2007 May 30. Erratum in: Nature. 2008 Jan 3;451(7174):102.

PMID:
17538624
2.

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.

Kim TW, Staschke K, Bulek K, Yao J, Peters K, Oh KH, Vandenburg Y, Xiao H, Qian W, Hamilton T, Min B, Sen G, Gilmour R, Li X.

J Exp Med. 2007 May 14;204(5):1025-36. Epub 2007 Apr 30.

3.

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling.

O'Neill LA, Bowie AG.

Nat Rev Immunol. 2007 May;7(5):353-64. Review.

PMID:
17457343
4.

The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.

Sheedy FJ, O'Neill LA.

J Leukoc Biol. 2007 Aug;82(2):196-203. Epub 2007 Apr 20. Review.

PMID:
17449723
5.

Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance.

Medvedev AE, Piao W, Shoenfelt J, Rhee SH, Chen H, Basu S, Wahl LM, Fenton MJ, Vogel SN.

J Biol Chem. 2007 Jun 1;282(22):16042-53. Epub 2007 Mar 28.

6.

Structure and function of Toll receptors and their ligands.

Gay NJ, Gangloff M.

Annu Rev Biochem. 2007;76:141-65. Review.

PMID:
17362201
7.

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

Miggin SM, Pålsson-McDermott E, Dunne A, Jefferies C, Pinteaux E, Banahan K, Murphy C, Moynagh P, Yamamoto M, Akira S, Rothwell N, Golenbock D, Fitzgerald KA, O'Neill LA.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3372-7. Epub 2007 Feb 20. Erratum in: Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17600.

8.

TLR signaling.

Kawai T, Akira S.

Semin Immunol. 2007 Feb;19(1):24-32. Epub 2007 Feb 1. Review.

PMID:
17275323
9.

Protein kinase Cdelta binds TIRAP/Mal to participate in TLR signaling.

Kubo-Murai M, Hazeki K, Sukenobu N, Yoshikawa K, Nigorikawa K, Inoue K, Yamamoto T, Matsumoto M, Seya T, Inoue N, Hazeki O.

Mol Immunol. 2007 Mar;44(9):2257-64. Epub 2006 Dec 11.

PMID:
17161867
10.

A phosphorylation site in the Toll-like receptor 5 TIR domain is required for inflammatory signalling in response to flagellin.

Ivison SM, Khan MA, Graham NR, Bernales CQ, Kaleem A, Tirling CO, Cherkasov A, Steiner TS.

Biochem Biophys Res Commun. 2007 Jan 26;352(4):936-41. Epub 2006 Dec 5.

PMID:
17157808
11.

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.

Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG.

J Biol Chem. 2007 Feb 9;282(6):4102-12. Epub 2006 Nov 29.

12.

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

Carty M, Goodbody R, Schröder M, Stack J, Moynagh PN, Bowie AG.

Nat Immunol. 2006 Oct;7(10):1074-81. Epub 2006 Sep 10.

PMID:
16964262
13.

Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity.

Doyle SL, O'Neill LA.

Biochem Pharmacol. 2006 Oct 30;72(9):1102-13. Epub 2006 Aug 22. Review.

PMID:
16930560
14.

Toll-like receptors as molecular switches.

Gay NJ, Gangloff M, Weber AN.

Nat Rev Immunol. 2006 Sep;6(9):693-8. doi: 10.1038/nri1916. Epub 2006 Aug 18. Review.

PMID:
16917510
15.

Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.

McGettrick AF, Brint EK, Palsson-McDermott EM, Rowe DC, Golenbock DT, Gay NJ, Fitzgerald KA, O'Neill LA.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9196-201. Epub 2006 Jun 6.

16.
17.

Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease.

Medvedev AE, Sabroe I, Hasday JD, Vogel SN.

J Endotoxin Res. 2006;12(3):133-50. Review.

PMID:
16719986
18.

Toll-like receptor function and signaling.

Kaisho T, Akira S.

J Allergy Clin Immunol. 2006 May;117(5):979-87; quiz 988. Epub 2006 Apr 3. Review.

PMID:
16675322
19.

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6299-304. Epub 2006 Apr 7.

20.

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O'Neill LA.

J Biol Chem. 2006 Apr 14;281(15):10489-95. Epub 2006 Jan 26. Erratum in: J Biol Chem. 2016 Dec 9;291(50):26240.

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