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Items: 1 to 20 of 50

1.

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction.

Morino K, Petersen KF, Shulman GI.

Diabetes. 2006 Dec;55 Suppl 2:S9-S15. Review.

2.

Evaluation of the role of nuclear factor-kappaB signaling in liver injury using genetic animal models.

Luedde T, Beraza N, Trautwein C.

J Gastroenterol Hepatol. 2006 Oct;21 Suppl 3:S43-6. Review.

PMID:
16958671
3.

c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity.

Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M, Hui L, Wagner EF.

Genes Dev. 2006 Aug 15;20(16):2306-14.

4.

Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress.

Bloch-Damti A, Potashnik R, Gual P, Le Marchand-Brustel Y, Tanti JF, Rudich A, Bashan N.

Diabetologia. 2006 Oct;49(10):2463-73. Epub 2006 Aug 3.

PMID:
16896943
5.

Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity.

Wu JJ, Roth RJ, Anderson EJ, Hong EG, Lee MK, Choi CS, Neufer PD, Shulman GI, Kim JK, Bennett AM.

Cell Metab. 2006 Jul;4(1):61-73.

6.

Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing.

auf dem Keller U, Huber M, Beyer TA, K├╝min A, Siemes C, Braun S, Bugnon P, Mitropoulos V, Johnson DA, Johnson JA, Hohl D, Werner S.

Mol Cell Biol. 2006 May;26(10):3773-84.

7.

Reactive oxygen species have a causal role in multiple forms of insulin resistance.

Houstis N, Rosen ED, Lander ES.

Nature. 2006 Apr 13;440(7086):944-8.

PMID:
16612386
8.

Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways.

Schwabe RF, Brenner DA.

Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G583-9. Review.

9.

Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout.

Desbois-Mouthon C, Wendum D, Cadoret A, Rey C, Leneuve P, Blaise A, Housset C, Tronche F, Le Bouc Y, Holzenberger M.

FASEB J. 2006 Apr;20(6):773-5. Epub 2006 Feb 16.

PMID:
16484330
10.

Apoptosis and necrosis in the liver: a tale of two deaths?

Malhi H, Gores GJ, Lemasters JJ.

Hepatology. 2006 Feb;43(2 Suppl 1):S31-44. Review.

PMID:
16447272
11.

Ethanol reduces p38 kinase activation and cyclin D1 protein expression after partial hepatectomy in rats.

Hsu MK, Qiao L, Ho V, Zhang BH, Zhang H, Teoh N, Dent P, Farrell GC.

J Hepatol. 2006 Feb;44(2):375-82. Epub 2005 Aug 26.

PMID:
16226824
12.

Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.

Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC.

Cancer Res. 2005 Jun 1;65(11):4799-808.

13.

The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.

Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB.

Cancer Res. 2005 Jun 1;65(11):4789-98.

14.

The activation of Akt/PKB signaling pathway and cell survival.

Song G, Ouyang G, Bao S.

J Cell Mol Med. 2005 Jan-Mar;9(1):59-71. Review.

15.

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases.

Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M.

Cell. 2005 Mar 11;120(5):649-61.

16.

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia.

Xu Z, Chen L, Leung L, Yen TS, Lee C, Chan JY.

Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4120-5. Epub 2005 Feb 28.

17.

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB.

Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE.

Nat Med. 2005 Feb;11(2):183-90. Epub 2005 Jan 30.

18.

Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance.

Zick Y.

Sci STKE. 2005 Jan 25;2005(268):pe4. Review.

PMID:
15671481
19.

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.

Shteyer E, Liao Y, Muglia LJ, Hruz PW, Rudnick DA.

Hepatology. 2004 Dec;40(6):1322-32.

PMID:
15565660
20.

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species.

Ventura JJ, Cogswell P, Flavell RA, Baldwin AS Jr, Davis RJ.

Genes Dev. 2004 Dec 1;18(23):2905-15. Epub 2004 Nov 15.

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