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Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway.

Dreyer HC, Glynn EL, Lujan HL, Fry CS, DiCarlo SE, Rasmussen BB.

J Appl Physiol (1985). 2008 Jan;104(1):27-33. Epub 2007 Sep 20.


Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle.

Louis E, Raue U, Yang Y, Jemiolo B, Trappe S.

J Appl Physiol (1985). 2007 Nov;103(5):1744-51. Epub 2007 Sep 6.


Nutrient signalling in the regulation of human muscle protein synthesis.

Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Cadenas JG, Yoshizawa F, Volpi E, Rasmussen BB.

J Physiol. 2007 Jul 15;582(Pt 2):813-23. Epub 2007 May 3.


Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage.

Wilkinson SB, Tarnopolsky MA, Macdonald MJ, Macdonald JR, Armstrong D, Phillips SM.

Am J Clin Nutr. 2007 Apr;85(4):1031-40. Erratum in: Am J Clin Nutr. 2013 Aug;98(2):512.


The rapid activation of protein synthesis by growth hormone requires signaling through mTOR.

Hayashi AA, Proud CG.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1647-55. Epub 2007 Feb 6.


Eukaryotic initiation factor 2B and its role in alterations in mRNA translation that occur under a number of pathophysiological and physiological conditions.

Kubica N, Jefferson LS, Kimball SR.

Prog Nucleic Acid Res Mol Biol. 2006;81:271-96. Review. No abstract available.


Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

Dreyer HC, Fujita S, Cadenas JG, Chinkes DL, Volpi E, Rasmussen BB.

J Physiol. 2006 Oct 15;576(Pt 2):613-24. Epub 2006 Jul 27.


Maximal lengthening contractions increase p70 S6 kinase phosphorylation in human skeletal muscle in the absence of nutritional supply.

Eliasson J, Elfegoun T, Nilsson J, Köhnke R, Ekblom B, Blomstrand E.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1197-205. Epub 2006 Jul 11.


A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly.

Katsanos CS, Kobayashi H, Sheffield-Moore M, Aarsland A, Wolfe RR.

Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E381-7. Epub 2006 Feb 28.


New functions for amino acids: effects on gene transcription and translation.

Kimball SR, Jefferson LS.

Am J Clin Nutr. 2006 Feb;83(2):500S-507S. Review.


Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise.

Blomstrand E, Eliasson J, Karlsson HK, Köhnke R.

J Nutr. 2006 Jan;136(1 Suppl):269S-73S. Review.


Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exercise.

Cuthbertson DJ, Babraj J, Smith K, Wilkes E, Fedele MJ, Esser K, Rennie M.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E731-8. Epub 2005 Nov 1.


Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

Nobukuni T, Joaquin M, Roccio M, Dann SG, Kim SY, Gulati P, Byfield MP, Backer JM, Natt F, Bos JL, Zwartkruis FJ, Thomas G.

Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14238-43. Epub 2005 Sep 21.


hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.

Byfield MP, Murray JT, Backer JM.

J Biol Chem. 2005 Sep 23;280(38):33076-82. Epub 2005 Jul 27.


Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle.

Cuthbertson D, Smith K, Babraj J, Leese G, Waddell T, Atherton P, Wackerhage H, Taylor PM, Rennie MJ.

FASEB J. 2005 Mar;19(3):422-4. Epub 2004 Dec 13.


Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects.

Koopman R, Wagenmakers AJ, Manders RJ, Zorenc AH, Senden JM, Gorselink M, Keizer HA, van Loon LJ.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E645-53. Epub 2004 Nov 23.


Effect of an amino acid, protein, and carbohydrate mixture on net muscle protein balance after resistance exercise.

Borsheim E, Aarsland A, Wolfe RR.

Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):255-71.


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