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Items: 1 to 20 of 42


Sugar binding induces an outward facing conformation of LacY.

Smirnova I, Kasho V, Choe JY, Altenbach C, Hubbell WL, Kaback HR.

Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16504-9. Epub 2007 Oct 9.


Single-molecule FRET reveals sugar-induced conformational dynamics in LacY.

Majumdar DS, Smirnova I, Kasho V, Nir E, Kong X, Weiss S, Kaback HR.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12640-5. Epub 2007 May 14.


Site-directed alkylation and the alternating access model for LacY.

Kaback HR, Dunten R, Frillingos S, Venkatesan P, Kwaw I, Zhang W, Ermolova N.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):491-4. Epub 2006 Dec 15.


An inward-facing conformation of a putative metal-chelate-type ABC transporter.

Pinkett HW, Lee AT, Lum P, Locher KP, Rees DC.

Science. 2007 Jan 19;315(5810):373-7. Epub 2006 Dec 7.


Energetics of ligand-induced conformational flexibility in the lactose permease of Escherichia coli.

Nie Y, Smirnova I, Kasho V, Kaback HR.

J Biol Chem. 2006 Nov 24;281(47):35779-84. Epub 2006 Sep 26.


Structure of a bacterial multidrug ABC transporter.

Dawson RJ, Locher KP.

Nature. 2006 Sep 14;443(7108):180-5. Epub 2006 Aug 30.


Lessons from lactose permease.

Guan L, Kaback HR.

Annu Rev Biophys Biomol Struct. 2006;35:67-91. Review.


Structure of the multidrug transporter EmrD from Escherichia coli.

Yin Y, He X, Szewczyk P, Nguyen T, Chang G.

Science. 2006 May 5;312(5774):741-4. Erratum in: Science. 2007 Sep 21;317(5845):1682.


Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY.

Mirza O, Guan L, Verner G, Iwata S, Kaback HR.

EMBO J. 2006 Mar 22;25(6):1177-83. Epub 2006 Mar 9. Erratum in: EMBO J. 2006 May 3;25(9):2038.


Manipulating phospholipids for crystallization of a membrane transport protein.

Guan L, Smirnova IN, Verner G, Nagamori S, Kaback HR.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1723-6. Epub 2006 Jan 30. Erratum in: Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):6073. Nagamoni, Shushi [corrected to Nagamori, Shushi].


Crystallization of a mammalian membrane protein overexpressed in Saccharomyces cerevisiae.

Jidenko M, Nielsen RC, Sørensen TL, Møller JV, le Maire M, Nissen P, Jaxel C.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11687-91. Epub 2005 Aug 8.


Crystal structure of a mammalian voltage-dependent Shaker family K+ channel.

Long SB, Campbell EB, Mackinnon R.

Science. 2005 Aug 5;309(5736):897-903. Epub 2005 Jul 7.


Interhelical packing modulates conformational flexibility in the lactose permease of Escherichia coli.

Ermolova NV, Smirnova IN, Kasho VN, Kaback HR.

Biochemistry. 2005 May 31;44(21):7669-77.


Lipids in membrane protein structures.

Palsdottir H, Hunte C.

Biochim Biophys Acta. 2004 Nov 3;1666(1-2):2-18. Review.


Sugar recognition by the lactose permease of Escherichia coli.

Vázquez-Ibar JL, Guan L, Weinglass AB, Verner G, Gordillo R, Kaback HR.

J Biol Chem. 2004 Nov 19;279(47):49214-21. Epub 2004 Sep 13.


Binding affinity of lactose permease is not altered by the H+ electrochemical gradient.

Guan L, Kaback HR.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12148-52. Epub 2004 Aug 10.


Three-dimensional crystallization of the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily.

Lemieux MJ, Song J, Kim MJ, Huang Y, Villa A, Auer M, Li XD, Wang DN.

Protein Sci. 2003 Dec;12(12):2748-56.


Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli.

Huang Y, Lemieux MJ, Song J, Auer M, Wang DN.

Science. 2003 Aug 1;301(5633):616-20.


Structure and mechanism of the lactose permease of Escherichia coli.

Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S.

Science. 2003 Aug 1;301(5633):610-5.


A defined protein-detergent-lipid complex for crystallization of integral membrane proteins: The cytochrome b6f complex of oxygenic photosynthesis.

Zhang H, Kurisu G, Smith JL, Cramer WA.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5160-3. Epub 2003 Apr 17.

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