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Items: 1 to 20 of 53


Leading-edge research: PtdIns(3,4,5)P3 and directed migration.

Franca-Koh J, Kamimura Y, Devreotes PN.

Nat Cell Biol. 2007 Jan;9(1):15-7. No abstract available.


Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth.

Miyamoto Y, Yamauchi J, Sanbe A, Tanoue A.

Exp Cell Res. 2007 Feb 15;313(4):791-804. Epub 2006 Dec 6.


Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.

Handa Y, Suzuki M, Ohya K, Iwai H, Ishijima N, Koleske AJ, Fukui Y, Sasakawa C.

Nat Cell Biol. 2007 Jan;9(1):121-8. Epub 2006 Dec 17.


The Scribble and Par complexes in polarity and migration: friends or foes?

Humbert PO, Dow LE, Russell SM.

Trends Cell Biol. 2006 Dec;16(12):622-30. Epub 2006 Oct 25. Review.


Dock4 is regulated by RhoG and promotes Rac-dependent cell migration.

Hiramoto K, Negishi M, Katoh H.

Exp Cell Res. 2006 Dec 10;312(20):4205-16. Epub 2006 Sep 16.


The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18.

Watabe-Uchida M, John KA, Janas JA, Newey SE, Van Aelst L.

Neuron. 2006 Sep 21;51(6):727-39.


Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42.

Lin Q, Yang W, Baird D, Feng Q, Cerione RA.

J Biol Chem. 2006 Nov 17;281(46):35253-62. Epub 2006 Sep 12.


DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis.

Kunisaki Y, Nishikimi A, Tanaka Y, Takii R, Noda M, Inayoshi A, Watanabe K, Sanematsu F, Sasazuki T, Sasaki T, Fukui Y.

J Cell Biol. 2006 Aug 28;174(5):647-52.


DOCK2 is required in T cell precursors for development of Valpha14 NK T cells.

Kunisaki Y, Tanaka Y, Sanui T, Inayoshi A, Noda M, Nakayama T, Harada M, Taniguchi M, Sasazuki T, Fukui Y.

J Immunol. 2006 Apr 15;176(8):4640-5.


Systematic analysis of the transcriptional switch inducing migration of border cells.

Borghese L, Fletcher G, Mathieu J, Atzberger A, Eades WC, Cagan RL, Rørth P.

Dev Cell. 2006 Apr;10(4):497-508. Erratum in: Dev Cell. 2009 Aug;17(2):299.


Elmo1 inhibits ubiquitylation of Dock180.

Makino Y, Tsuda M, Ichihara S, Watanabe T, Sakai M, Sawa H, Nagashima K, Hatakeyama S, Tanaka S.

J Cell Sci. 2006 Mar 1;119(Pt 5):923-32.


Activation of Rac1 by RhoG regulates cell migration.

Katoh H, Hiramoto K, Negishi M.

J Cell Sci. 2006 Jan 1;119(Pt 1):56-65. Epub 2005 Dec 8.


CZH proteins: a new family of Rho-GEFs.

Meller N, Merlot S, Guda C.

J Cell Sci. 2005 Nov 1;118(Pt 21):4937-46. Review.


Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection.

Jiang H, Pan F, Erickson LM, Jang MS, Sanui T, Kunisaki Y, Sasazuki T, Kobayashi M, Fukui Y.

J Exp Med. 2005 Oct 17;202(8):1121-30.


The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1.

Santy LC, Ravichandran KS, Casanova JE.

Curr Biol. 2005 Oct 11;15(19):1749-54.


Rho GTPases: biochemistry and biology.

Jaffe AB, Hall A.

Annu Rev Cell Dev Biol. 2005;21:247-69. Review.


A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.

Côté JF, Motoyama AB, Bush JA, Vuori K.

Nat Cell Biol. 2005 Aug;7(8):797-807. Epub 2005 Jul 17.


Identification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.

Yokoyama N, deBakker CD, Zappacosta F, Huddleston MJ, Annan RS, Ravichandran KS, Miller WT.

Biochemistry. 2005 Jun 21;44(24):8841-9.


A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.

Lu M, Kinchen JM, Rossman KL, Grimsley C, Hall M, Sondek J, Hengartner MO, Yajnik V, Ravichandran KS.

Curr Biol. 2005 Feb 22;15(4):371-7.


Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

Nishikimi A, Meller N, Uekawa N, Isobe K, Schwartz MA, Maruyama M.

FEBS Lett. 2005 Feb 14;579(5):1039-46. Epub 2005 Jan 13.

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