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Items: 1 to 20 of 60

2.

Overview: the long and winding road to understanding Alzheimer's disease.

Herz J.

Neuron. 2007 Feb 15;53(4):477-9. Review. No abstract available.

3.

Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease.

Lee JH, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M, Arriaga A, Stern Y, Tycko B, Rogaeva E, Wakutani Y, Kawarai T, St George-Hyslop P, Mayeux R.

Arch Neurol. 2006 Nov;63(11):1591-8.

PMID:
17101828
4.

The UBL domain of PLIC-1 regulates aggresome formation.

Heir R, Ablasou C, Dumontier E, Elliott M, Fagotto-Kaufmann C, Bedford FK.

EMBO Rep. 2006 Dec;7(12):1252-8. Epub 2006 Nov 3.

5.

Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion.

Hiltunen M, Lu A, Thomas AV, Romano DM, Kim M, Jones PB, Xie Z, Kounnas MZ, Wagner SL, Berezovska O, Hyman BT, Tesco G, Bertram L, Tanzi RE.

J Biol Chem. 2006 Oct 27;281(43):32240-53. Epub 2006 Aug 31.

6.

Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes.

Hébert SS, Serneels L, Tolia A, Craessaerts K, Derks C, Filippov MA, Müller U, De Strooper B.

EMBO Rep. 2006 Jul;7(7):739-45. Epub 2006 May 19.

7.

Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures.

Kamboh MI, Minster RL, Feingold E, DeKosky ST.

Mol Psychiatry. 2006 Mar;11(3):273-9.

PMID:
16302009
8.

A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.

Hass MR, Yankner BA.

J Biol Chem. 2005 Nov 4;280(44):36895-904. Epub 2005 Aug 15.

9.

Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors.

Ficklin MB, Zhao S, Feng G.

J Biol Chem. 2005 Oct 7;280(40):34088-95. Epub 2005 Aug 9.

10.

The ubiquilin 1 gene and Alzheimer's disease.

Slifer MA, Martin ER, Haines JL, Pericak-Vance MA.

N Engl J Med. 2005 Jun 30;352(26):2752-3; author reply 2752-3. No abstract available.

11.
12.

Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.

Pardossi-Piquard R, Petit A, Kawarai T, Sunyach C, Alves da Costa C, Vincent B, Ring S, D'Adamio L, Shen J, Müller U, St George Hyslop P, Checler F.

Neuron. 2005 May 19;46(4):541-54.

13.

Family-based association between Alzheimer's disease and variants in UBQLN1.

Bertram L, Hiltunen M, Parkinson M, Ingelsson M, Lange C, Ramasamy K, Mullin K, Menon R, Sampson AJ, Hsiao MY, Elliott KJ, Velicelebi G, Moscarillo T, Hyman BT, Wagner SL, Becker KD, Blacker D, Tanzi RE.

N Engl J Med. 2005 Mar 3;352(9):884-94.

14.

Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.

Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S, Moore P, Wavrant DeVrieze F, Myers A, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, O'Donovan M, Jones L, Hardy J, Goate A, Lovestone S, Owen M, Williams J.

Am J Med Genet B Neuropsychiatr Genet. 2005 May 5;135B(1):24-32.

PMID:
15729734
15.
16.

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor.

von Rotz RC, Kohli BM, Bosset J, Meier M, Suzuki T, Nitsch RM, Konietzko U.

J Cell Sci. 2004 Sep 1;117(Pt 19):4435-48.

17.

Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein.

Lanni C, Mazzucchelli M, Porrello E, Govoni S, Racchi M.

Eur J Biochem. 2004 Jul;271(14):3068-75.

18.

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.

Allinson TM, Parkin ET, Condon TP, Schwager SL, Sturrock ED, Turner AJ, Hooper NM.

Eur J Biochem. 2004 Jun;271(12):2539-47.

19.

Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.

Saura CA, Choi SY, Beglopoulos V, Malkani S, Zhang D, Shankaranarayana Rao BS, Chattarji S, Kelleher RJ 3rd, Kandel ER, Duff K, Kirkwood A, Shen J.

Neuron. 2004 Apr 8;42(1):23-36.

20.

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.

Cao X, Südhof TC.

J Biol Chem. 2004 Jun 4;279(23):24601-11. Epub 2004 Mar 24.

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