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Items: 1 to 20 of 46


Genetic disorders of programmed cell death in the immune system.

Bidère N, Su HC, Lenardo MJ.

Annu Rev Immunol. 2006;24:321-52. Review.


Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation.

Zhong F, Davis MC, McColl KS, Distelhorst CW.

J Cell Biol. 2006 Jan 2;172(1):127-37.


Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis.

Madesh M, Hawkins BJ, Milovanova T, Bhanumathy CD, Joseph SK, Ramachandrarao SP, Sharma K, Kurosaki T, Fisher AB.

J Cell Biol. 2005 Sep 26;170(7):1079-90.


The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R.

White C, Li C, Yang J, Petrenko NB, Madesh M, Thompson CB, Foskett JK.

Nat Cell Biol. 2005 Oct;7(10):1021-8. Epub 2005 Sep 18. Erratum in: Nat Cell Biol. 2006 Mar;8(3):299.


Cellular FLICE-inhibitory protein is required for T cell survival and cycling.

Chau H, Wong V, Chen NJ, Huang HL, Lin WJ, Mirtsos C, Elford AR, Bonnard M, Wakeham A, You-Ten AI, Lemmers B, Salmena L, Pellegrini M, Hakem R, Mak TW, Ohashi P, Yeh WC.

J Exp Med. 2005 Aug 1;202(3):405-13. Epub 2005 Jul 25.


Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum.

Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):105-10. Epub 2004 Dec 21.


Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, Velez P, Distelhorst CW.

J Cell Biol. 2004 Jul 19;166(2):193-203.


T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation.

Jackson SH, Devadas S, Kwon J, Pinto LA, Williams MS.

Nat Immunol. 2004 Aug;5(8):818-27. Epub 2004 Jul 18.


Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.

Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB.

J Cell Biol. 2003 Jul 7;162(1):59-69.


Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity.

Salmena L, Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K, Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, Wakeham A, Bouchard D, Yeh WC, McGlade JC, Ohashi PS, Hakem R.

Genes Dev. 2003 Apr 1;17(7):883-95. Epub 2003 Mar 21.


BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis.

Scorrano L, Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T, Korsmeyer SJ.

Science. 2003 Apr 4;300(5616):135-9. Epub 2003 Mar 6.


The cellular and molecular basis of store-operated calcium entry.

Venkatachalam K, van Rossum DB, Patterson RL, Ma HT, Gill DL.

Nat Cell Biol. 2002 Nov;4(11):E263-72. Review.


Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more.

Marsden VS, Strasser A.

Annu Rev Immunol. 2003;21:71-105. Epub 2001 Dec 19. Review.


Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.

Rathmell JC, Lindsten T, Zong WX, Cinalli RM, Thompson CB.

Nat Immunol. 2002 Oct;3(10):932-9. Epub 2002 Sep 3.


The CD28 signaling pathway regulates glucose metabolism.

Frauwirth KA, Riley JL, Harris MH, Parry RV, Rathmell JC, Plas DR, Elstrom RL, June CH, Thompson CB.

Immunity. 2002 Jun;16(6):769-77.


Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors.

Li C, Fox CJ, Master SR, Bindokas VP, Chodosh LA, Thompson CB.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9830-5. Epub 2002 Jul 12.


T-cell signalling and autoimmunity: molecular mechanisms of disease.

Ohashi PS.

Nat Rev Immunol. 2002 Jun;2(6):427-38. Review.


Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses.

Foulds KE, Zenewicz LA, Shedlock DJ, Jiang J, Troy AE, Shen H.

J Immunol. 2002 Feb 15;168(4):1528-32.


Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction.

Krauss S, Brand MD, Buttgereit F.

Immunity. 2001 Oct;15(4):497-502. Review.

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