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Items: 1 to 20 of 21

1.

Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.

Hukkanen J, Jacob P 3rd, Benowitz NL.

Clin Pharmacol Ther. 2006 Nov;80(5):522-30.

PMID:
17112808
2.

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

Benowitz NL, Swan GE, Jacob P 3rd, Lessov-Schlaggar CN, Tyndale RF.

Clin Pharmacol Ther. 2006 Nov;80(5):457-67.

PMID:
17112802
3.

Specific detection of anabasine, nicotine, and nicotine metabolites in urine by liquid chromatography-tandem mass spectrometry.

Hoofnagle AN, Laha TJ, Rainey PM, Sadrzadeh SM.

Am J Clin Pathol. 2006 Dec;126(6):880-7.

PMID:
17074683
4.

Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation.

Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz N.

Clin Pharmacol Ther. 2006 Jun;79(6):600-8. Epub 2006 May 11.

PMID:
16765148
5.

Trends in the exposure of nonsmokers in the U.S. population to secondhand smoke: 1988-2002.

Pirkle JL, Bernert JT, Caudill SP, Sosnoff CS, Pechacek TF.

Environ Health Perspect. 2006 Jun;114(6):853-8.

7.

Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.

von Weymarn LB, Brown KM, Murphy SE.

J Pharmacol Exp Ther. 2006 Jan;316(1):295-303. Epub 2005 Sep 27.

8.

Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence.

Swan GE, Benowitz NL, Lessov CN, Jacob P 3rd, Tyndale RF, Wilhelmsen K.

Pharmacogenet Genomics. 2005 Feb;15(2):115-25.

PMID:
15861035
9.

Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.

Murphy SE, Raulinaitis V, Brown KM.

Drug Metab Dispos. 2005 Aug;33(8):1166-73. Epub 2005 Apr 28.

10.

Implications of CYP2A6 genetic variation for smoking behaviors and nicotine dependence.

Malaiyandi V, Sellers EM, Tyndale RF.

Clin Pharmacol Ther. 2005 Mar;77(3):145-58. Review.

PMID:
15735609
11.

Metabolism and disposition kinetics of nicotine.

Hukkanen J, Jacob P 3rd, Benowitz NL.

Pharmacol Rev. 2005 Mar;57(1):79-115. Review.

14.

The measurement of nicotine in human plasma by high-performance liquid chromatography-electrospray-tandem mass spectrometry.

Taylor PJ, Forrest KK, Landsberg PG, Mitchell C, Pillans PI.

Ther Drug Monit. 2004 Oct;26(5):563-8.

PMID:
15385840
15.

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity.

Dempsey D, Tutka P, Jacob P 3rd, Allen F, Schoedel K, Tyndale RF, Benowitz NL.

Clin Pharmacol Ther. 2004 Jul;76(1):64-72.

PMID:
15229465
16.

The neurobiology of tobacco dependence: a commentary.

Balfour DJ.

Respiration. 2002;69(1):7-11. Review.

PMID:
11844955
18.
19.

Nicotine addiction.

Benowitz NL.

Prim Care. 1999 Sep;26(3):611-31. Review.

PMID:
10436290
20.

Development and validation of sensitive method for determination of serum cotinine in smokers and nonsmokers by liquid chromatography/atmospheric pressure ionization tandem mass spectrometry.

Bernert JT Jr, Turner WE, Pirkle JL, Sosnoff CS, Akins JR, Waldrep MK, Ann Q, Covey TR, Whitfield WE, Gunter EW, Miller BB, Patterson DG Jr, Needham LL, Hannon WH, Sampson EJ.

Clin Chem. 1997 Dec;43(12):2281-91.

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