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Items: 1 to 20 of 44


Gut microbes out of control in HIV infection.

Haynes BF.

Nat Med. 2006 Dec;12(12):1351-2. No abstract available.


Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytotoxic T-cell and IgG2a response.

Bourquin C, Schmidt L, Hornung V, Wurzenberger C, Anz D, Sandholzer N, Schreiber S, Voelkl A, Hartmann G, Endres S.

Blood. 2007 Apr 1;109(7):2953-60.


Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC.

Nat Med. 2006 Dec;12(12):1365-71. Epub 2006 Nov 19.


5'-Triphosphate RNA is the ligand for RIG-I.

Hornung V, Ellegast J, Kim S, Brzózka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G.

Science. 2006 Nov 10;314(5801):994-7. Epub 2006 Oct 12.


RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates.

Pichlmair A, Schulz O, Tan CP, Näslund TI, Liljeström P, Weber F, Reis e Sousa C.

Science. 2006 Nov 10;314(5801):997-1001. Epub 2006 Oct 12.


Dynamics of T cells subsets and lymphoproliferative responses during structured treatment interruption cycles and after definitive interruption of HAART in early chronic HIV type-1-infected patients.

Libois A, López A, Garcia F, Castro P, Maleno MJ, García A, Climent N, Arnedo M, Gallart T, Gatell JM, Plana M.

AIDS Res Hum Retroviruses. 2006 Jul;22(7):657-66.


T cell-independent, TLR-induced IL-12p70 production in primary human monocytes.

Bekeredjian-Ding I, Roth SI, Gilles S, Giese T, Ablasser A, Hornung V, Endres S, Hartmann G.

J Immunol. 2006 Jun 15;176(12):7438-46.


Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists.

Gorski KS, Waller EL, Bjornton-Severson J, Hanten JA, Riter CL, Kieper WC, Gorden KB, Miller JS, Vasilakos JP, Tomai MA, Alkan SS.

Int Immunol. 2006 Jul;18(7):1115-26. Epub 2006 May 25.


Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells.

Levy O, Suter EE, Miller RL, Wessels MR.

Blood. 2006 Aug 15;108(4):1284-90. Epub 2006 Apr 25.


HIV disease: fallout from a mucosal catastrophe?

Brenchley JM, Price DA, Douek DC.

Nat Immunol. 2006 Mar;7(3):235-9. Review.


Control of B-cell responses by Toll-like receptors.

Pasare C, Medzhitov R.

Nature. 2005 Nov 17;438(7066):364-8.


Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus.

Barrat FJ, Meeker T, Gregorio J, Chan JH, Uematsu S, Akira S, Chang B, Duramad O, Coffman RL.

J Exp Med. 2005 Oct 17;202(8):1131-9.


Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions.

Beignon AS, McKenna K, Skoberne M, Manches O, DaSilva I, Kavanagh DG, Larsson M, Gorelick RJ, Lifson JD, Bhardwaj N.

J Clin Invest. 2005 Nov;115(11):3265-75. Epub 2005 Oct 13.


Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells.

Romagnani C, Della Chiesa M, Kohler S, Moewes B, Radbruch A, Moretta L, Moretta A, Thiel A.

Eur J Immunol. 2005 Aug;35(8):2452-8.


Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts.

Silvestri G, Fedanov A, Germon S, Kozyr N, Kaiser WJ, Garber DA, McClure H, Feinberg MB, Staprans SI.

J Virol. 2005 Apr;79(7):4043-54.


Pleiotropic function of Toll-like receptors.

Kaisho T, Akira S.

Microbes Infect. 2004 Dec;6(15):1388-94. Review.


Toll-like receptors in innate immunity.

Takeda K, Akira S.

Int Immunol. 2005 Jan;17(1):1-14. Review.


CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.

Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, Nguyen PL, Khoruts A, Larson M, Haase AT, Douek DC.

J Exp Med. 2004 Sep 20;200(6):749-59. Epub 2004 Sep 13.


Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract.

Mehandru S, Poles MA, Tenner-Racz K, Horowitz A, Hurley A, Hogan C, Boden D, Racz P, Markowitz M.

J Exp Med. 2004 Sep 20;200(6):761-70. Epub 2004 Sep 13.


Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.

Rutz M, Metzger J, Gellert T, Luppa P, Lipford GB, Wagner H, Bauer S.

Eur J Immunol. 2004 Sep;34(9):2541-50.

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