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Items: 1 to 20 of 36


Plasma membrane is the site of productive HIV-1 particle assembly.

Jouvenet N, Neil SJ, Bess C, Johnson MC, Virgen CA, Simon SM, Bieniasz PD.

PLoS Biol. 2006 Dec;4(12):e435.


Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry.

Chattopadhyay PK, Price DA, Harper TF, Betts MR, Yu J, Gostick E, Perfetto SP, Goepfert P, Koup RA, De Rosa SC, Bruchez MP, Roederer M.

Nat Med. 2006 Aug;12(8):972-7. Epub 2006 Jul 23.


Assembly of infectious HIV-1 in human epithelial and T-lymphoblastic cell lines.

Grigorov B, Arcanger F, Roingeard P, Darlix JL, Muriaux D.

J Mol Biol. 2006 Jun 16;359(4):848-62. Epub 2006 Apr 25.


The Vif and Vpr accessory proteins independently cause HIV-1-induced T cell cytopathicity and cell cycle arrest.

Sakai K, Dimas J, Lenardo MJ.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3369-74. Epub 2006 Feb 21.


Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection.

Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M.

Nature. 2005 Apr 28;434(7037):1093-7.


Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

Li Q, Duan L, Estes JD, Ma ZM, Rourke T, Wang Y, Reilly C, Carlis J, Miller CJ, Haase AT.

Nature. 2005 Apr 28;434(7037):1148-52.


Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells.

Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD.

Cancer Res. 2005 Mar 15;65(6):2076-81.


Ritonavir does not inhibit calpain in vitro.

Cuerrier D, Nie Z, Badley AD, Davies PL.

Biochem Biophys Res Commun. 2005 Feb 4;327(1):208-11.


CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.

Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, Nguyen PL, Khoruts A, Larson M, Haase AT, Douek DC.

J Exp Med. 2004 Sep 20;200(6):749-59. Epub 2004 Sep 13.


Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract.

Mehandru S, Poles MA, Tenner-Racz K, Horowitz A, Hurley A, Hogan C, Boden D, Racz P, Markowitz M.

J Exp Med. 2004 Sep 20;200(6):761-70. Epub 2004 Sep 13.


T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis.

Brenchley JM, Hill BJ, Ambrozak DR, Price DA, Guenaga FJ, Casazza JP, Kuruppu J, Yazdani J, Migueles SA, Connors M, Roederer M, Douek DC, Koup RA.

J Virol. 2004 Feb;78(3):1160-8.


Infectious HIV-1 assembles in late endosomes in primary macrophages.

Pelchen-Matthews A, Kramer B, Marsh M.

J Cell Biol. 2003 Aug 4;162(3):443-55. Epub 2003 Jul 28.


Apoptosis as an HIV strategy to escape immune attack.

Gougeon ML.

Nat Rev Immunol. 2003 May;3(5):392-404. Review.


A unified model for apical caspase activation.

Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM, Ricci JE, Edris WA, Sutherlin DP, Green DR, Salvesen GS.

Mol Cell. 2003 Feb;11(2):529-41.


HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation.

Nie Z, Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, Krammer PH, Sekaly RP, Badley AD.

Cell Death Differ. 2002 Nov;9(11):1172-84.


Cell killing by HIV-1 protease.

Blanco R, Carrasco L, Ventoso I.

J Biol Chem. 2003 Jan 10;278(2):1086-93. Epub 2002 Oct 4.


HIV preferentially infects HIV-specific CD4+ T cells.

Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, Koup RA.

Nature. 2002 May 2;417(6884):95-8.


Evidence for increased T cell turnover and decreased thymic output in HIV infection.

Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA.

J Immunol. 2001 Dec 1;167(11):6663-8.


HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation.

Ventoso I, Blanco R, Perales C, Carrasco L.

Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12966-71. Epub 2001 Oct 23.


Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice.

Miura Y, Misawa N, Maeda N, Inagaki Y, Tanaka Y, Ito M, Kayagaki N, Yamamoto N, Yagita H, Mizusawa H, Koyanagi Y.

J Exp Med. 2001 Mar 5;193(5):651-60.

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