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Items: 1 to 20 of 37

1.

Observation of ligand binding to cytochrome P450 BM-3 by means of solid-state NMR spectroscopy.

Jovanovic T, McDermott AE.

J Am Chem Soc. 2005 Oct 12;127(40):13816-21.

PMID:
16201802
2.

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen.

Yano JK, Hsu MH, Griffin KJ, Stout CD, Johnson EF.

Nat Struct Mol Biol. 2005 Sep;12(9):822-3. Epub 2005 Aug 7.

PMID:
16086027
3.

Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions.

Atkins WM.

Annu Rev Pharmacol Toxicol. 2005;45:291-310. Review.

PMID:
15832445
4.

An electrostatically driven conformational transition is involved in the mechanisms of substrate binding and cooperativity in cytochrome P450eryF.

Davydov DR, Botchkareva AE, Kumar S, He YQ, Halpert JR.

Biochemistry. 2004 Jun 1;43(21):6475-85.

PMID:
15157081
5.
7.

An open conformation of mammalian cytochrome P450 2B4 at 1.6-A resolution.

Scott EE, He YA, Wester MR, White MA, Chin CC, Halpert JR, Johnson EF, Stout CD.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13196-201. Epub 2003 Oct 16.

9.

Crystal structure of human cytochrome P450 2C9 with bound warfarin.

Williams PA, Cosme J, Ward A, Angove HC, Matak Vinković D, Jhoti H.

Nature. 2003 Jul 24;424(6947):464-8. Epub 2003 Jul 13.

PMID:
12861225
10.

Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling.

Spatzenegger M, Liu H, Wang Q, Debarber A, Koop DR, Halpert JR.

J Pharmacol Exp Ther. 2003 Jan;304(1):477-87.

11.

Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam.

Prasad S, Mitra S.

Biochemistry. 2002 Dec 10;41(49):14499-508.

PMID:
12463748
12.

Use of kinetic isotope effects to delineate the role of phenylalanine 87 in P450(BM-3).

Rock DA, Boitano AE, Wahlstrom JL, Rock DA, Jones JP.

Bioorg Chem. 2002 Apr;30(2):107-18.

PMID:
12020135
14.

Active site characteristics of CYP4B1 probed with aromatic ligands.

Henne KR, Fisher MB, Iyer KR, Lang DH, Trager WF, Rettie AE.

Biochemistry. 2001 Jul 24;40(29):8597-605.

PMID:
11456500
15.
16.

Conformational modulation of human cytochrome P450 2E1 by ethanol and other substrates: a CO flash photolysis study.

Smith SV, Koley AP, Dai R, Robinson RC, Leong H, Markowitz A, Friedman FK.

Biochemistry. 2000 May 16;39(19):5731-7.

PMID:
10801323
17.

CYP2A6: a human coumarin 7-hydroxylase.

Pelkonen O, Rautio A, Raunio H, Pasanen M.

Toxicology. 2000 Apr 3;144(1-3):139-47. Review.

PMID:
10781881
18.

Dual role of human cytochrome P450 3A4 residue Phe-304 in substrate specificity and cooperativity.

Domanski TL, He YA, Harlow GR, Halpert JR.

J Pharmacol Exp Ther. 2000 May;293(2):585-91.

20.

Deuterium magic angle spinning studies of substrates bound to cytochrome P450.

Lee H, Ortiz de Montellano PR, McDermott AE.

Biochemistry. 1999 Aug 17;38(33):10808-13.

PMID:
10451377

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