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Items: 1 to 20 of 42


Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.

Lin J, Yang R, Tarr PT, Wu PH, Handschin C, Li S, Yang W, Pei L, Uldry M, Tontonoz P, Newgard CB, Spiegelman BM.

Cell. 2005 Jan 28;120(2):261-73.


Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.

Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jäger S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM.

Cell. 2004 Oct 1;119(1):121-35.


New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving the LRP130 protein.

Labialle S, Dayan G, Gayet L, Rigal D, Gambrelle J, Baggetto LG.

Nucleic Acids Res. 2004 Jul 22;32(13):3864-76. Print 2004.


PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M.

Nat Med. 2004 May;10(5):530-4. Epub 2004 Apr 25. Erratum in: Nat Med. 2004 Jul;7(10):755.


LRP130, a single-stranded DNA/RNA-binding protein, localizes at the outer nuclear and endoplasmic reticulum membrane, and interacts with mRNA in vivo.

Tsuchiya N, Fukuda H, Nakashima K, Nagao M, Sugimura T, Nakagama H.

Biochem Biophys Res Commun. 2004 May 7;317(3):736-43.


IQGAP1 binds ERK2 and modulates its activity.

Roy M, Li Z, Sacks DB.

J Biol Chem. 2004 Apr 23;279(17):17329-37. Epub 2004 Feb 17.


Subacute necrotizing encephalomyelopathy in an infant.


J Neurol Neurosurg Psychiatry. 1951 Aug;14(3):216-21. No abstract available.


Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.

Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE, Medeiros DM, Valencik ML, McDonald JA, Kelly DP.

Circ Res. 2004 Mar 5;94(4):525-33. Epub 2004 Jan 15.


Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

Wallberg AE, Yamamura S, Malik S, Spiegelman BM, Roeder RG.

Mol Cell. 2003 Nov;12(5):1137-49.


Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.

Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM.

Nature. 2003 May 29;423(6939):550-5. Epub 2003 May 18.


Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells.

St-Pierre J, Lin J, Krauss S, Tarr PT, Yang R, Newgard CB, Spiegelman BM.

J Biol Chem. 2003 Jul 18;278(29):26597-603. Epub 2003 May 6.


Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis.

Rhee J, Inoue Y, Yoon JC, Puigserver P, Fan M, Gonzalez FJ, Spiegelman BM.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4012-7. Epub 2003 Mar 21.


Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics.

Mootha VK, Lepage P, Miller K, Bunkenborg J, Reich M, Hjerrild M, Delmonte T, Villeneuve A, Sladek R, Xu F, Mitchell GA, Morin C, Mann M, Hudson TJ, Robinson B, Rioux JD, Lander ES.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):605-10. Epub 2003 Jan 14.


Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver.

Miyake K, Ogawa W, Matsumoto M, Nakamura T, Sakaue H, Kasuga M.

J Clin Invest. 2002 Nov;110(10):1483-91.


Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

Nakae J, Biggs WH 3rd, Kitamura T, Cavenee WK, Wright CV, Arden KC, Accili D.

Nat Genet. 2002 Oct;32(2):245-53. Epub 2002 Sep 3.


Isolation and mass spectrometry of transcription factor complexes.

Sebastiaan Winkler G, Lacomis L, Philip J, Erdjument-Bromage H, Svejstrup JQ, Tempst P.

Methods. 2002 Mar;26(3):260-9.


Nuclear activators and coactivators in mammalian mitochondrial biogenesis.

Scarpulla RC.

Biochim Biophys Acta. 2002 Jun 7;1576(1-2):1-14. Review.


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