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Items: 1 to 20 of 21

1.

Hypoxia requires notch signaling to maintain the undifferentiated cell state.

Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J, Ruas JL, Poellinger L, Lendahl U, Bondesson M.

Dev Cell. 2005 Nov;9(5):617-28.

2.

Proline hydroxylation and gene expression.

Kaelin WG.

Annu Rev Biochem. 2005;74:115-28. Review.

PMID:
15952883
3.

The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

Ozer A, Wu LC, Bruick RK.

Proc Natl Acad Sci U S A. 2005 May 24;102(21):7481-6. Epub 2005 May 16.

4.

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL.

Mol Cell. 2005 Feb 18;17(4):503-12.

5.

Signaling to NF-kappaB.

Hayden MS, Ghosh S.

Genes Dev. 2004 Sep 15;18(18):2195-224. Review.

6.

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ.

J Biol Chem. 2004 Oct 8;279(41):42719-25. Epub 2004 Aug 9. Erratum in: J Biol Chem. 2004 Dec 24;279(52):54974.

7.

Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways.

Zampetaki A, Mitsialis SA, Pfeilschifter J, Kourembanas S.

FASEB J. 2004 Jul;18(10):1090-2. Epub 2004 May 7.

PMID:
15132979
8.

Oxygen sensing by HIF hydroxylases.

Schofield CJ, Ratcliffe PJ.

Nat Rev Mol Cell Biol. 2004 May;5(5):343-54. Review. No abstract available.

PMID:
15122348
9.

Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.

Linke S, Stojkoski C, Kewley RJ, Booker GW, Whitelaw ML, Peet DJ.

J Biol Chem. 2004 Apr 2;279(14):14391-7. Epub 2004 Jan 20.

10.

Collagens, modifying enzymes and their mutations in humans, flies and worms.

Myllyharju J, Kivirikko KI.

Trends Genet. 2004 Jan;20(1):33-43. Review.

PMID:
14698617
11.

Consensus-derived structural determinants of the ankyrin repeat motif.

Mosavi LK, Minor DL Jr, Peng ZY.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16029-34. Epub 2002 Dec 2.

12.

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.

Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK.

Genes Dev. 2002 Jun 15;16(12):1466-71.

13.

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.

Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ.

J Biol Chem. 2002 Jul 19;277(29):26351-5. Epub 2002 May 31.

14.
15.

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1.

Semenza GL.

Annu Rev Cell Dev Biol. 1999;15:551-78. Review.

PMID:
10611972
16.

NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2.

Yang JP, Hori M, Takahashi N, Kawabe T, Kato H, Okamoto T.

Oncogene. 1999 Sep 16;18(37):5177-86.

17.

The ankyrin repeat: a diversity of interactions on a common structural framework.

Sedgwick SG, Smerdon SJ.

Trends Biochem Sci. 1999 Aug;24(8):311-6. Review.

PMID:
10431175
18.

INK4 cell cycle inhibitors direct transcriptional inactivation of NF-kappaB.

Wolff B, Naumann M.

Oncogene. 1999 Apr 22;18(16):2663-6.

19.

SMART, a simple modular architecture research tool: identification of signaling domains.

Schultz J, Milpetz F, Bork P, Ponting CP.

Proc Natl Acad Sci U S A. 1998 May 26;95(11):5857-64.

20.

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells.

Schmedtje JF Jr, Ji YS, Liu WL, DuBois RN, Runge MS.

J Biol Chem. 1997 Jan 3;272(1):601-8.

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