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Items: 1 to 20 of 49


Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells.

Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG.

Blood. 2006 Apr 15;107(8):3212-20. Epub 2005 Dec 13.


Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

Yokosuka T, Sakata-Sogawa K, Kobayashi W, Hiroshima M, Hashimoto-Tane A, Tokunaga M, Dustin ML, Saito T.

Nat Immunol. 2005 Dec;6(12):1253-62. Epub 2005 Nov 6.


The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains.

Gimferrer I, Ibáñez A, Farnós M, Sarrias MR, Fenutría R, Roselló S, Zimmermann P, David G, Vives J, Serra-Pagès C, Lozano F.

J Immunol. 2005 Aug 1;175(3):1406-14.


Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses.

Risueño RM, Gil D, Fernández E, Sánchez-Madrid F, Alarcón B.

Blood. 2005 Jul 15;106(2):601-8. Epub 2005 Mar 24.


The SLP-76 family of adapter proteins.

Wu JN, Koretzky GA.

Semin Immunol. 2004 Dec;16(6):379-93. Review.


Expression and characterization of a novel CD6 ligand in cells derived from joint and epithelial tissues.

Saifullah MK, Fox DA, Sarkar S, Abidi SM, Endres J, Piktel J, Haqqi TM, Singer NG.

J Immunol. 2004 Nov 15;173(10):6125-33.


Relevance of CD6-mediated interactions in T cell activation and proliferation.

Gimferrer I, Calvo M, Mittelbrunn M, Farnós M, Sarrias MR, Enrich C, Vives J, Sánchez-Madrid F, Lozano F.

J Immunol. 2004 Aug 15;173(4):2262-70.


Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences.

Houtman JC, Higashimoto Y, Dimasi N, Cho S, Yamaguchi H, Bowden B, Regan C, Malchiodi EL, Mariuzza R, Schuck P, Appella E, Samelson LE.

Biochemistry. 2004 Apr 13;43(14):4170-8.


Frontline: Optimal T cell activation requires the engagement of CD6 and CD166.

Hassan NJ, Barclay AN, Brown MH.

Eur J Immunol. 2004 Apr;34(4):930-40.


Subunit interface residues of glutathione S-transferase A1-1 that are important in the monomer-dimer equilibrium.

Vargo MA, Nguyen L, Colman RF.

Biochemistry. 2004 Mar 30;43(12):3327-35.


Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76.

Harkiolaki M, Lewitzky M, Gilbert RJ, Jones EY, Bourette RP, Mouchiroud G, Sondermann H, Moarefi I, Feller SM.

EMBO J. 2003 Jun 2;22(11):2571-82.


CD5 inhibits signaling at the immunological synapse without impairing its formation.

Brossard C, Semichon M, Trautmann A, Bismuth G.

J Immunol. 2003 May 1;170(9):4623-9.


Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85.

Hutchings NJ, Clarkson N, Chalkley R, Barclay AN, Brown MH.

J Biol Chem. 2003 Jun 20;278(25):22396-403. Epub 2003 Apr 10.


OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation.

Castro MA, Nunes RJ, Oliveira MI, Tavares PA, Simões C, Parnes JR, Moreira A, Carmo AM.

J Leukoc Biol. 2003 Jan;73(1):183-90.


The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells.

Gimferrer I, Farnós M, Calvo M, Mittelbrunn M, Enrich C, Sánchez-Madrid F, Vives J, Lozano F.

J Biol Chem. 2003 Mar 7;278(10):8564-71. Epub 2002 Dec 8.


T cell receptor ligation induces the formation of dynamically regulated signaling assemblies.

Bunnell SC, Hong DI, Kardon JR, Yamazaki T, McGlade CJ, Barr VA, Samelson LE.

J Cell Biol. 2002 Sep 30;158(7):1263-75.


CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain.

Bhandoola A, Bosselut R, Yu Q, Cowan ML, Feigenbaum L, Love PE, Singer A.

Eur J Immunol. 2002 Jun;32(6):1811-7.

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