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Items: 17


SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models.

Golas JM, Lucas J, Etienne C, Golas J, Discafani C, Sridharan L, Boghaert E, Arndt K, Ye F, Boschelli DH, Li F, Titsch C, Huselton C, Chaudhary I, Boschelli F.

Cancer Res. 2005 Jun 15;65(12):5358-64.


Mechanisms of cancer cell invasion.

Sahai E.

Curr Opin Genet Dev. 2005 Feb;15(1):87-96. Review.


MAP kinases and cell migration.

Huang C, Jacobson K, Schaller MD.

J Cell Sci. 2004 Sep 15;117(Pt 20):4619-28. Review.


Cell migration: integrating signals from front to back.

Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.

Science. 2003 Dec 5;302(5651):1704-9. Review.


Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening.

Aza-Blanc P, Cooper CL, Wagner K, Batalov S, Deveraux QL, Cooke MP.

Mol Cell. 2003 Sep;12(3):627-37.


JNK phosphorylates paxillin and regulates cell migration.

Huang C, Rajfur Z, Borchers C, Schaller MD, Jacobson K.

Nature. 2003 Jul 10;424(6945):219-23.


Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing.

Javelaud D, Laboureau J, Gabison E, Verrecchia F, Mauviel A.

J Biol Chem. 2003 Jul 4;278(27):24624-8. Epub 2003 May 1.


Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.

Goldberg DR, Butz T, Cardozo MG, Eckner RJ, Hammach A, Huang J, Jakes S, Kapadia S, Kashem M, Lukas S, Morwick TM, Panzenbeck M, Patel U, Pav S, Peet GW, Peterson JD, Prokopowicz AS 3rd, Snow RJ, Sellati R, Takahashi H, Tan J, Tschantz MA, Wang XJ, Wang Y, Wolak J, Xiong P, Moss N.

J Med Chem. 2003 Apr 10;46(8):1337-49.


The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion.

Wright JH, Wang X, Manning G, LaMere BJ, Le P, Zhu S, Khatry D, Flanagan PM, Buckley SD, Whyte DB, Howlett AR, Bischoff JR, Lipson KE, Jallal B.

Mol Cell Biol. 2003 Mar;23(6):2068-82.


Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers.

Wiener JR, Windham TC, Estrella VC, Parikh NU, Thall PF, Deavers MT, Bast RC, Mills GB, Gallick GE.

Gynecol Oncol. 2003 Jan;88(1):73-9.


A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans.

Poinat P, De Arcangelis A, Sookhareea S, Zhu X, Hedgecock EM, Labouesse M, Georges-Labouesse E.

Curr Biol. 2002 Apr 16;12(8):622-31.


Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells.

Burke WM, Jin X, Lin HJ, Huang M, Liu R, Reynolds RK, Lin J.

Oncogene. 2001 Nov 29;20(55):7925-34.


Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).

Xue Y, Wang X, Li Z, Gotoh N, Chapman D, Skolnik EY.

Development. 2001 May;128(9):1559-72.


A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway.

Yao Z, Zhou G, Wang XS, Brown A, Diener K, Gan H, Tan TH.

J Biol Chem. 1999 Jan 22;274(4):2118-25.


Identification of a novel inhibitor of mitogen-activated protein kinase kinase.

Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM.

J Biol Chem. 1998 Jul 17;273(29):18623-32.


Cell migration: a physically integrated molecular process.

Lauffenburger DA, Horwitz AF.

Cell. 1996 Feb 9;84(3):359-69. Review. No abstract available.


The initiation of cell division in a contact-inhibited mammalian cell line.

Todaro GJ, Lazar GK, Green H.

J Cell Physiol. 1965 Dec;66(3):325-33. No abstract available.


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