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Items: 1 to 20 of 35

1.

Bleomycin induces alveolar epithelial cell death through JNK-dependent activation of the mitochondrial death pathway.

Lee VY, Schroedl C, Brunelle JK, Buccellato LJ, Akinci OI, Kaneto H, Snyder C, Eisenbart J, Budinger GR, Chandel NS.

Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L521-8.

2.

Pulmonary fibrosis: searching for model answers.

Chua F, Gauldie J, Laurent GJ.

Am J Respir Cell Mol Biol. 2005 Jul;33(1):9-13. Review.

PMID:
15964990
3.

Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury.

Budinger GR, Chandel NS, Donnelly HK, Eisenbart J, Oberoi M, Jain M.

Intensive Care Med. 2005 Jan;31(1):121-8. Epub 2004 Nov 24.

PMID:
15565360
4.

Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor.

Bonniaud P, Margetts PJ, Kolb M, Schroeder JA, Kapoun AM, Damm D, Murphy A, Chakravarty S, Dugar S, Higgins L, Protter AA, Gauldie J.

Am J Respir Crit Care Med. 2005 Apr 15;171(8):889-98. Epub 2004 Nov 24.

PMID:
15563636
5.

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis.

Lee CG, Cho SJ, Kang MJ, Chapoval SP, Lee PJ, Noble PW, Yehualaeshet T, Lu B, Flavell RA, Milbrandt J, Homer RJ, Elias JA.

J Exp Med. 2004 Aug 2;200(3):377-89.

6.

The pathophysiology of mitochondrial cell death.

Green DR, Kroemer G.

Science. 2004 Jul 30;305(5684):626-9. Review.

PMID:
15286356
7.

Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis.

Bonniaud P, Kolb M, Galt T, Robertson J, Robbins C, Stampfli M, Lavery C, Margetts PJ, Roberts AB, Gauldie J.

J Immunol. 2004 Aug 1;173(3):2099-108.

8.

Cell death: critical control points.

Danial NN, Korsmeyer SJ.

Cell. 2004 Jan 23;116(2):205-19. Review.

9.
10.

Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway.

Tsuburai T, Suzuki M, Nagashima Y, Suzuki S, Inoue S, Hasiba T, Ueda A, Ikehara K, Matsuse T, Ishigatsubo Y.

Hum Gene Ther. 2002 Nov 1;13(16):1945-60.

PMID:
12449100
11.

A new direction in the pathogenesis of idiopathic pulmonary fibrosis?

Gauldie J, Kolb M, Sime PJ.

Respir Res. 2002;3:1. Epub 2001 Sep 26. Review.

12.

Idiopathic pulmonary fibrosis.

Gross TJ, Hunninghake GW.

N Engl J Med. 2001 Aug 16;345(7):517-25. Review.

13.

TGF-beta is a critical mediator of acute lung injury.

Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, Sheppard D.

J Clin Invest. 2001 Jun;107(12):1537-44.

14.

Pulmonary fibrosis: a cellular overreaction or a failure of communication?

Sheppard D.

J Clin Invest. 2001 Jun;107(12):1501-2. No abstract available.

15.

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.

Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ.

Science. 2001 Apr 27;292(5517):727-30.

16.

Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy.

Selman M, King TE, Pardo A; American Thoracic Society; European Respiratory Society; American College of Chest Physicians.

Ann Intern Med. 2001 Jan 16;134(2):136-51. Review.

PMID:
11177318
17.

Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor.

Kuwano K, Kunitake R, Maeyama T, Hagimoto N, Kawasaki M, Matsuba T, Yoshimi M, Inoshima I, Yoshida K, Hara N.

Am J Physiol Lung Cell Mol Physiol. 2001 Feb;280(2):L316-25.

18.

The Fas/Fas-ligand system is not required for bleomycin-induced pulmonary fibrosis in mice.

Aoshiba K, Yasui S, Tamaoki J, Nagai A.

Am J Respir Crit Care Med. 2000 Aug;162(2 Pt 1):695-700.

PMID:
10934108
19.

Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor.

Wang R, Ibarra-Sunga O, Verlinski L, Pick R, Uhal BD.

Am J Physiol Lung Cell Mol Physiol. 2000 Jul;279(1):L143-51.

20.

The acute respiratory distress syndrome.

Ware LB, Matthay MA.

N Engl J Med. 2000 May 4;342(18):1334-49. Review. No abstract available.

PMID:
10793167

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