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Items: 1 to 20 of 26

1.

Crystal structure of human cytochrome P450 2D6.

Rowland P, Blaney FE, Smyth MG, Jones JJ, Leydon VR, Oxbrow AK, Lewis CJ, Tennant MG, Modi S, Eggleston DS, Chenery RJ, Bridges AM.

J Biol Chem. 2006 Mar 17;281(11):7614-22. Epub 2005 Dec 13.

2.

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen.

Yano JK, Hsu MH, Griffin KJ, Stout CD, Johnson EF.

Nat Struct Mol Biol. 2005 Sep;12(9):822-3. Epub 2005 Aug 7.

PMID:
16086027
3.

Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors.

Jiang JG, Chen CL, Card JW, Yang S, Chen JX, Fu XN, Ning YG, Xiao X, Zeldin DC, Wang DW.

Cancer Res. 2005 Jun 1;65(11):4707-15.

4.

Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways.

Wang Y, Wei X, Xiao X, Hui R, Card JW, Carey MA, Wang DW, Zeldin DC.

J Pharmacol Exp Ther. 2005 Aug;314(2):522-32. Epub 2005 Apr 19.

5.

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution.

Yano JK, Wester MR, Schoch GA, Griffin KJ, Stout CD, Johnson EF.

J Biol Chem. 2004 Sep 10;279(37):38091-4. Epub 2004 Jul 16.

6.

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone.

Williams PA, Cosme J, Vinkovic DM, Ward A, Angove HC, Day PJ, Vonrhein C, Tickle IJ, Jhoti H.

Science. 2004 Jul 30;305(5684):683-6. Epub 2004 Jul 15.

7.

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution.

Wester MR, Yano JK, Schoch GA, Yang C, Griffin KJ, Stout CD, Johnson EF.

J Biol Chem. 2004 Aug 20;279(34):35630-7. Epub 2004 Jun 4.

8.

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site.

Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF.

J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15.

9.

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function.

Spector AA, Fang X, Snyder GD, Weintraub NL.

Prog Lipid Res. 2004 Jan;43(1):55-90. Review.

PMID:
14636671
10.

Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.

Pfister SL, Spitzbarth N, Zeldin DC, Lafite P, Mansuy D, Campbell WB.

Arch Biochem Biophys. 2003 Dec 1;420(1):142-52.

PMID:
14622984
11.

Crystal structure of human cytochrome P450 2C9 with bound warfarin.

Williams PA, Cosme J, Ward A, Angove HC, Matak Vinković D, Jhoti H.

Nature. 2003 Jul 24;424(6947):464-8. Epub 2003 Jul 13.

PMID:
12861225
12.
13.

Verapamil: metabolism in cultures of primary human coronary arterial endothelial cells.

Borlak J, Walles M, Levsen K, Thum T.

Drug Metab Dispos. 2003 Jul;31(7):888-91.

14.

Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole.

Matsumoto S, Hirama T, Matsubara T, Nagata K, Yamazoe Y.

Drug Metab Dispos. 2002 Nov;30(11):1240-5.

15.

Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes.

Hashizume T, Imaoka S, Mise M, Terauchi Y, Fujii T, Miyazaki H, Kamataki T, Funae Y.

J Pharmacol Exp Ther. 2002 Jan;300(1):298-304.

16.

Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs.

Mancy A, Antignac M, Minoletti C, Dijols S, Mouries V, Duong NT, Battioni P, Dansette PM, Mansuy D.

Biochemistry. 1999 Oct 26;38(43):14264-70.

PMID:
10572000
17.

Cytochrome P450 2C is an EDHF synthase in coronary arteries.

Fisslthaler B, Popp R, Kiss L, Potente M, Harder DR, Fleming I, Busse R.

Nature. 1999 Sep 30;401(6752):493-7.

PMID:
10519554
18.

P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues.

Scarborough PE, Ma J, Qu W, Zeldin DC.

Drug Metab Rev. 1999 Feb;31(1):205-34. Review.

PMID:
10065373
19.
20.

Further characterization of the expression in liver and catalytic activity of CYP2B6.

Ekins S, Vandenbranden M, Ring BJ, Gillespie JS, Yang TJ, Gelboin HV, Wrighton SA.

J Pharmacol Exp Ther. 1998 Sep;286(3):1253-9.

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