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Items: 1 to 20 of 45

1.

Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase.

DerMardirossian C, Schnelzer A, Bokoch GM.

Mol Cell. 2004 Jul 2;15(1):117-27.

2.

Pak-1 expression increases with progression of colorectal carcinomas to metastasis.

Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, Pemberton JO, Konicek S, Hom J, Marshall M, Graff JR.

Clin Cancer Res. 2004 May 15;10(10):3448-56.

3.

Activation of the tumor suppressor merlin modulates its interaction with lipid rafts.

Stickney JT, Bacon WC, Rojas M, Ratner N, Ip W.

Cancer Res. 2004 Apr 15;64(8):2717-24.

4.

E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

Qian X, Karpova T, Sheppard AM, McNally J, Lowy DR.

EMBO J. 2004 Apr 21;23(8):1739-48. Epub 2004 Apr 1.

5.

Integrins regulate Rac targeting by internalization of membrane domains.

del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA.

Science. 2004 Feb 6;303(5659):839-42.

6.

Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

Surace EI, Haipek CA, Gutmann DH.

Oncogene. 2004 Jan 15;23(2):580-7.

PMID:
14724586
7.

Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.

Kissil JL, Wilker EW, Johnson KC, Eckman MS, Yaffe MB, Jacks T.

Mol Cell. 2003 Oct;12(4):841-9.

8.

p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.

Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK, Kumar R.

J Biol Chem. 2004 Jan 9;279(2):1422-8. Epub 2003 Oct 6.

9.

Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma.

Schraml P, Schwerdtfeger G, Burkhalter F, Raggi A, Schmidt D, Ruffalo T, King W, Wilber K, Mihatsch MJ, Moch H.

Am J Pathol. 2003 Sep;163(3):985-92.

10.

Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148.

Grazia Lampugnani M, Zanetti A, Corada M, Takahashi T, Balconi G, Breviario F, Orsenigo F, Cattelino A, Kemler R, Daniel TO, Dejana E.

J Cell Biol. 2003 May 26;161(4):793-804.

11.

NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.

Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey AI.

Genes Dev. 2003 May 1;17(9):1090-100. Epub 2003 Apr 14.

12.

Biology of the p21-activated kinases.

Bokoch GM.

Annu Rev Biochem. 2003;72:743-81. Epub 2003 Mar 27. Review.

PMID:
12676796
13.

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor.

Vermeer PD, Einwalter LA, Moninger TO, Rokhlina T, Kern JA, Zabner J, Welsh MJ.

Nature. 2003 Mar 20;422(6929):322-6.

PMID:
12646923
14.

RHO-GTPases and cancer.

Sahai E, Marshall CJ.

Nat Rev Cancer. 2002 Feb;2(2):133-42. Review.

PMID:
12635176
15.

Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.

Speck O, Hughes SC, Noren NK, Kulikauskas RM, Fehon RG.

Nature. 2003 Jan 2;421(6918):83-7.

PMID:
12511959
16.

Rho GTPases in cell biology.

Etienne-Manneville S, Hall A.

Nature. 2002 Dec 12;420(6916):629-35. Review.

PMID:
12478284
17.

Cell-cell adhesion and signalling.

Braga VM.

Curr Opin Cell Biol. 2002 Oct;14(5):546-56. Review.

PMID:
12231348
18.

Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene.

Johnson KC, Kissil JL, Fry JL, Jacks T.

Oncogene. 2002 Sep 5;21(39):5990-7.

20.
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