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Items: 1 to 20 of 48

1.

Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels.

Hashimoto K, Durbin JE, Zhou W, Collins RD, Ho SB, Kolls JK, Dubin PJ, Sheller JR, Goleniewska K, O'Neal JF, Olson SJ, Mitchell D, Graham BS, Peebles RS Jr.

J Allergy Clin Immunol. 2005 Sep;116(3):550-7.

PMID:
16159623
2.

Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.

Stark MA, Huo Y, Burcin TL, Morris MA, Olson TS, Ley K.

Immunity. 2005 Mar;22(3):285-94.

3.

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.

Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ.

J Exp Med. 2005 Jan 17;201(2):233-40.

4.

IL-12 and IL-23: master regulators of innate and adaptive immunity.

Langrish CL, McKenzie BS, Wilson NJ, de Waal Malefyt R, Kastelein RA, Cua DJ.

Immunol Rev. 2004 Dec;202:96-105. Review.

PMID:
15546388
5.

Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis.

Ferrari-Lacraz S, Zanelli E, Neuberg M, Donskoy E, Kim YS, Zheng XX, Hancock WW, Maslinski W, Li XC, Strom TB, Moll T.

J Immunol. 2004 Nov 1;173(9):5818-26.

6.

Interleukin-17 family members and inflammation.

Kolls JK, Lindén A.

Immunity. 2004 Oct;21(4):467-76. Review.

7.

STAT4 is a critical mediator of early innate immune responses against pulmonary Klebsiella infection.

Deng JC, Zeng X, Newstead M, Moore TA, Tsai WC, Thannickal VJ, Standiford TJ.

J Immunol. 2004 Sep 15;173(6):4075-83.

8.

IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.

Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R.

J Immunol. 2004 Sep 1;173(5):3482-91.

9.

Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment.

Ruddy MJ, Shen F, Smith JB, Sharma A, Gaffen SL.

J Leukoc Biol. 2004 Jul;76(1):135-44. Epub 2004 Apr 23.

PMID:
15107456
10.

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria.

Verreck FA, de Boer T, Langenberg DM, Hoeve MA, Kramer M, Vaisberg E, Kastelein R, Kolk A, de Waal-Malefyt R, Ottenhoff TH.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4560-5. Epub 2004 Mar 19.

11.

Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice.

Ghilardi N, Kljavin N, Chen Q, Lucas S, Gurney AL, De Sauvage FJ.

J Immunol. 2004 Mar 1;172(5):2827-33.

12.

The role of defensins in lung biology and therapy.

Cole AM, Waring AJ.

Am J Respir Med. 2002;1(4):249-59. Review.

PMID:
14720045
13.

Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

Happel KI, Zheng M, Young E, Quinton LJ, Lockhart E, Ramsay AJ, Shellito JE, Schurr JR, Bagby GJ, Nelson S, Kolls JK.

J Immunol. 2003 May 1;170(9):4432-6.

14.

Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop.

Chen Y, Thai P, Zhao YH, Ho YS, DeSouza MM, Wu R.

J Biol Chem. 2003 May 9;278(19):17036-43. Epub 2003 Mar 6.

15.

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.

Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD.

Nature. 2003 Feb 13;421(6924):744-8.

PMID:
12610626
16.
17.
18.

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17.

Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL.

J Biol Chem. 2003 Jan 17;278(3):1910-4. Epub 2002 Nov 3.

19.

Divergent role of gamma interferon in a murine model of pulmonary versus systemic Klebsiella pneumoniae infection.

Moore TA, Perry ML, Getsoian AG, Newstead MW, Standiford TJ.

Infect Immun. 2002 Nov;70(11):6310-8.

20.

New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.

Hurst SD, Muchamuel T, Gorman DM, Gilbert JM, Clifford T, Kwan S, Menon S, Seymour B, Jackson C, Kung TT, Brieland JK, Zurawski SM, Chapman RW, Zurawski G, Coffman RL.

J Immunol. 2002 Jul 1;169(1):443-53.

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