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Items: 1 to 20 of 55

1.

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.

Harrington LS, Findlay GM, Gray A, Tolkacheva T, Wigfield S, Rebholz H, Barnett J, Leslie NR, Cheng S, Shepherd PR, Gout I, Downes CP, Lamb RF.

J Cell Biol. 2004 Jul 19;166(2):213-23. Epub 2004 Jul 12.

2.

Serum insulin-like growth factor-I, insulin-like growth factor binding protein-3, and the risk of pancreatic cancer death.

Lin Y, Tamakoshi A, Kikuchi S, Yagyu K, Obata Y, Ishibashi T, Kawamura T, Inaba Y, Kurosawa M, Motohashi Y, Ohno Y.

Int J Cancer. 2004 Jul 1;110(4):584-8.

3.

Tuberous sclerosis complex: from Drosophila to human disease.

Pan D, Dong J, Zhang Y, Gao X.

Trends Cell Biol. 2004 Feb;14(2):78-85. Review.

PMID:
15102439
4.

Cyclins and breast cancer.

Sutherland RL, Musgrove EA.

J Mammary Gland Biol Neoplasia. 2004 Jan;9(1):95-104. Review.

PMID:
15082921
5.

Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression.

Zhang X, Kamaraju S, Hakuno F, Kabuta T, Takahashi S, Sachdev D, Yee D.

Breast Cancer Res Treat. 2004 Jan;83(2):161-70.

PMID:
14997047
6.

Progesterone receptors in mammary gland development and tumorigenesis.

Conneely OM, Jericevic BM, Lydon JP.

J Mammary Gland Biol Neoplasia. 2003 Apr;8(2):205-14. Review.

PMID:
14635795
7.

Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases.

Lin EY, Jones JG, Li P, Zhu L, Whitney KD, Muller WJ, Pollard JW.

Am J Pathol. 2003 Nov;163(5):2113-26.

8.
9.

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation.

Schubert M, Brazil DP, Burks DJ, Kushner JA, Ye J, Flint CL, Farhang-Fallah J, Dikkes P, Warot XM, Rio C, Corfas G, White MF.

J Neurosci. 2003 Aug 6;23(18):7084-92.

10.

The insulin-like growth factor system and cancer.

LeRoith D, Roberts CT Jr.

Cancer Lett. 2003 Jun 10;195(2):127-37. Review.

PMID:
12767520
11.

Developmental and hormonal signals dramatically alter the localization and abundance of insulin receptor substrate proteins in the mammary gland.

Lee AV, Zhang P, Ivanova M, Bonnette S, Oesterreich S, Rosen JM, Grimm S, Hovey RC, Vonderhaar BK, Kahn CR, Torres D, George J, Mohsin S, Allred DC, Hadsell DL.

Endocrinology. 2003 Jun;144(6):2683-94.

PMID:
12746333
12.

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.

Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13571-6. Epub 2002 Sep 23.

13.

IRS proteins and the common path to diabetes.

White MF.

Am J Physiol Endocrinol Metab. 2002 Sep;283(3):E413-22. Review.

14.

Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer.

Sandhu MS, Dunger DB, Giovannucci EL.

J Natl Cancer Inst. 2002 Jul 3;94(13):972-80. Review.

PMID:
12096082
15.

The phosphoinositide 3-kinase pathway.

Cantley LC.

Science. 2002 May 31;296(5573):1655-7. Review.

PMID:
12040186
16.

Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease.

Hellawell GO, Turner GD, Davies DR, Poulsom R, Brewster SF, Macaulay VM.

Cancer Res. 2002 May 15;62(10):2942-50.

17.

Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin).

Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M.

J Natl Cancer Inst. 2001 Dec 19;93(24):1852-7.

PMID:
11752009
18.

Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect.

Albanell J, Baselga J.

J Natl Cancer Inst. 2001 Dec 19;93(24):1830-2. No abstract available.

PMID:
11752000
19.
20.

The IGF system and breast cancer.

Sachdev D, Yee D.

Endocr Relat Cancer. 2001 Sep;8(3):197-209. Review.

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