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Items: 1 to 20 of 51

1.

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis.

Redwine JM, Kosofsky B, Jacobs RE, Games D, Reilly JF, Morrison JH, Young WG, Bloom FE.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1381-6. Epub 2003 Jan 24.

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Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein.

Kim HJ, Chae SC, Lee DK, Chromy B, Lee SC, Park YC, Klein WL, Krafft GA, Hong ST.

FASEB J. 2003 Jan;17(1):118-20. Epub 2002 Nov 1.

PMID:
12424218
5.

Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites.

Sasaki A, Shoji M, Harigaya Y, Kawarabayashi T, Ikeda M, Naito M, Matsubara E, Abe K, Nakazato Y.

Virchows Arch. 2002 Oct;441(4):358-67. Epub 2002 May 1.

PMID:
12404061
6.

Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human beta-amyloid precursor protein.

Sánchez-Alavez M, Gallegos RA, Kalafut MA, Games D, Henriksen SJ, Criado JR.

Neurosci Lett. 2002 Sep 13;330(1):45-8.

PMID:
12213631
7.

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

Hardy J, Selkoe DJ.

Science. 2002 Jul 19;297(5580):353-6. Review. Erratum in: Science 2002 Sep 27;297(5590):2209.

PMID:
12130773
8.

Selective nicotinic receptor consequences in APP(SWE) transgenic mice.

Bednar I, Paterson D, Marutle A, Pham TM, Svedberg M, Hellström-Lindahl E, Mousavi M, Court J, Morris C, Perry E, Mohammed A, Zhang X, Nordberg A.

Mol Cell Neurosci. 2002 Jun;20(2):354-65.

PMID:
12093166
9.

Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.

Fodero LR, Sáez-Valero J, McLean CA, Martins RN, Beyreuther K, Masters CL, Robertson TA, Small DH.

J Neurochem. 2002 May;81(3):441-8.

10.

Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer's disease.

Bussière T, Friend PD, Sadeghi N, Wicinski B, Lin GI, Bouras C, Giannakopoulos P, Robakis NK, Morrison JH, Perl DP, Hof PR.

Neuroscience. 2002;112(1):75-91.

PMID:
12044473
11.

Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice.

Huitrón-Reséndiz S, Sánchez-Alavez M, Gallegos R, Berg G, Crawford E, Giacchino JL, Games D, Henriksen SJ, Criado JR.

Brain Res. 2002 Feb 22;928(1-2):126-37.

PMID:
11844479
12.

Alzheimer's disease and the amyloid cascade hypothesis: ten years on.

Sommer B.

Curr Opin Pharmacol. 2002 Feb;2(1):87-92. Review.

PMID:
11786314
13.

The evolution of A beta peptide burden in the APP23 transgenic mice: implications for A beta deposition in Alzheimer disease.

Kuo YM, Beach TG, Sue LI, Scott S, Layne KJ, Kokjohn TA, Kalback WM, Luehrs DC, Vishnivetskaya TA, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Weller RO, Roher AE.

Mol Med. 2001 Sep;7(9):609-18.

14.

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

Wang HW, Pasternak JF, Kuo H, Ristic H, Lambert MP, Chromy B, Viola KL, Klein WL, Stine WB, Krafft GA, Trommer BL.

Brain Res. 2002 Jan 11;924(2):133-40.

PMID:
11750898
15.

Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption.

Le R, Cruz L, Urbanc B, Knowles RB, Hsiao-Ashe K, Duff K, Irizarry MC, Stanley HE, Hyman BT.

J Neuropathol Exp Neurol. 2001 Aug;60(8):753-8.

PMID:
11487049
16.

Alzheimer's disease and Abeta toxicity: from top to bottom.

Small DH, Mok SS, Bornstein JC.

Nat Rev Neurosci. 2001 Aug;2(8):595-8. Review. No abstract available.

PMID:
11484003
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18.

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

Klein WL, Krafft GA, Finch CE.

Trends Neurosci. 2001 Apr;24(4):219-24. Review.

PMID:
11250006
19.

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG.

J Neurosci. 2001 Jan 15;21(2):372-81.

20.

Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.

Christie RH, Bacskai BJ, Zipfel WR, Williams RM, Kajdasz ST, Webb WW, Hyman BT.

J Neurosci. 2001 Feb 1;21(3):858-64.

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