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Items: 1 to 20 of 28

1.

Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia.

Splawski I, Timothy KW, Tateyama M, Clancy CE, Malhotra A, Beggs AH, Cappuccio FP, Sagnella GA, Kass RS, Keating MT.

Science. 2002 Aug 23;297(5585):1333-6.

2.

Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function.

Schram G, Pourrier M, Melnyk P, Nattel S.

Circ Res. 2002 May 17;90(9):939-50. Review.

3.

Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes.

Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, Hohnloser SH, Shimizu W, Schwartz PJ, Stanton M, Murray KT, Norris K, George AL Jr, Roden DM.

Circulation. 2002 Apr 23;105(16):1943-8.

4.

Clinical and molecular heterogeneity in the Brugada syndrome: a novel gene locus on chromosome 3.

Weiss R, Barmada MM, Nguyen T, Seibel JS, Cavlovich D, Kornblit CA, Angelilli A, Villanueva F, McNamara DM, London B.

Circulation. 2002 Feb 12;105(6):707-13.

5.

Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block.

Wang DW, Viswanathan PC, Balser JR, George AL Jr, Benson DW.

Circulation. 2002 Jan 22;105(3):341-6.

6.

Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes.

Viswanathan PC, Bezzina CR, George AL Jr, Roden DM, Wilde AA, Balser JR.

Circulation. 2001 Sep 4;104(10):1200-5.

7.

The heart SNPs a beat: polymorphisms in candidate genes for cardiovascular disease.

Daley GQ, Cargill M.

Trends Cardiovasc Med. 2001 Feb;11(2):60-6. Review.

PMID:
11530294
8.

Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes.

Rivolta I, Abriel H, Tateyama M, Liu H, Memmi M, Vardas P, Napolitano C, Priori SG, Kass RS.

J Biol Chem. 2001 Aug 17;276(33):30623-30. Epub 2001 Jun 15.

9.

A sodium-channel mutation causes isolated cardiac conduction disease.

Tan HL, Bink-Boelkens MT, Bezzina CR, Viswanathan PC, Beaufort-Krol GC, van Tintelen PJ, van den Berg MP, Wilde AA, Balser JR.

Nature. 2001 Feb 22;409(6823):1043-7.

PMID:
11234013
10.

Enhanced Na(+) channel intermediate inactivation in Brugada syndrome.

Wang DW, Makita N, Kitabatake A, Balser JR, George AL Jr.

Circ Res. 2000 Oct 13;87(8):E37-43.

11.

Genetic susceptibility to cardiovascular diseases.

Roses AD.

Am Heart J. 2000 Oct;140(4):S45-7. Review. No abstract available.

PMID:
11011323
12.

Pharmacogenetics and the treatment of cardiovascular disease.

Wilkins MR, Roses AD, Clifford CP.

Heart. 2000 Oct;84(4):353-4. No abstract available.

13.

A common polymorphism associated with antibiotic-induced cardiac arrhythmia.

Sesti F, Abbott GW, Wei J, Murray KT, Saksena S, Schwartz PJ, Priori SG, Roden DM, George AL Jr, Goldstein SA.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10613-8.

14.

The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection.

Saunders AM, Trowers MK, Shimkets RA, Blakemore S, Crowther DJ, Mansfield TA, Wallace DM, Strittmatter WJ, Roses AD.

Biochim Biophys Acta. 2000 Jul 26;1502(1):85-94. Review.

15.

Pharmacogenetics and the practice of medicine.

Roses AD.

Nature. 2000 Jun 15;405(6788):857-65. Review.

PMID:
10866212
16.

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel.

Veldkamp MW, Viswanathan PC, Bezzina C, Baartscheer A, Wilde AA, Balser JR.

Circ Res. 2000 May 12;86(9):E91-7.

17.

Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome.

Antzelevitch C, Yan GX, Shimizu W.

J Electrocardiol. 1999;32 Suppl:158-65. Review.

PMID:
10688320
18.

A single Na(+) channel mutation causing both long-QT and Brugada syndromes.

Bezzina C, Veldkamp MW, van Den Berg MP, Postma AV, Rook MB, Viersma JW, van Langen IM, Tan-Sindhunata G, Bink-Boelkens MT, van Der Hout AH, Mannens MM, Wilde AA.

Circ Res. 1999 Dec 3-17;85(12):1206-13.

19.

Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent.

Dumaine R, Towbin JA, Brugada P, Vatta M, Nesterenko DV, Nesterenko VV, Brugada J, Brugada R, Antzelevitch C.

Circ Res. 1999 Oct 29;85(9):803-9.

20.

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