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Items: 1 to 20 of 38

1.

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease.

Monteleone G, Kumberova A, Croft NM, McKenzie C, Steer HW, MacDonald TT.

J Clin Invest. 2001 Aug;108(4):601-9.

2.
3.

Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease.

Hahm KB, Im YH, Parks TW, Park SH, Markowitz S, Jung HY, Green J, Kim SJ.

Gut. 2001 Aug;49(2):190-8.

4.
5.

A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells.

Itoh H, Beck PL, Inoue N, Xavier R, Podolsky DK.

J Clin Invest. 1999 Dec;104(11):1539-47.

6.

Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation.

Koh TJ, Dockray GJ, Varro A, Cahill RJ, Dangler CA, Fox JG, Wang TC.

J Clin Invest. 1999 Apr;103(8):1119-26.

7.

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta.

Yang X, Letterio JJ, Lechleider RJ, Chen L, Hayman R, Gu H, Roberts AB, Deng C.

EMBO J. 1999 Mar 1;18(5):1280-91.

8.

Growth factors in inflammatory bowel disease.

Beck PL, Podolsky DK.

Inflamm Bowel Dis. 1999 Feb;5(1):44-60. Review.

PMID:
10028449
9.

Controlled release of TGF-beta1 impedes rat colon carcinogenesis in vivo.

Mikhailowski R, Shpitz B, Polak-Charcon S, Kost Y, Segal Y, Segal C, Fich A, Lamprecht SA.

Int J Cancer. 1998 Nov 23;78(5):618-23.

10.

Smad3 mutant mice develop metastatic colorectal cancer.

Zhu Y, Richardson JA, Parada LF, Graff JM.

Cell. 1998 Sep 18;94(6):703-14.

11.

Transfection of the type II TGF-beta receptor into colon cancer cells increases receptor expression, inhibits cell growth, and reduces the malignant phenotype.

MacKay SL, Auffenberg T, Tannahill CL, Ksontini R, Josephs MD, Nowak M, Moldawer LL, Copeland EM 3rd.

Ann Surg. 1998 Jun;227(6):781-9.

12.

Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma.

Bak AW, McKnight W, Li P, Del Soldato P, Calignano A, Cirino G, Wallace JL.

Life Sci. 1998;62(23):PL 367-73.

PMID:
9627095
13.

TGF-beta receptor signaling.

Derynck R, Feng XH.

Biochim Biophys Acta. 1997 Oct 24;1333(2):F105-50. Review. No abstract available.

PMID:
9395284
14.

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis.

Serra R, Johnson M, Filvaroff EH, LaBorde J, Sheehan DM, Derynck R, Moses HL.

J Cell Biol. 1997 Oct 20;139(2):541-52.

15.

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.

Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR.

Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2386-91.

17.

Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation.

Strober W, Kelsall B, Fuss I, Marth T, Ludviksson B, Ehrhardt R, Neurath M.

Immunol Today. 1997 Feb;18(2):61-4. Review.

PMID:
9057354
18.

A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms.

Souza RF, Lei J, Yin J, Appel R, Zou TT, Zhou X, Wang S, Rhyu MG, Cymes K, Chan O, Park WS, Krasna MJ, Greenwald BD, Cottrell J, Abraham JM, Simms L, Leggett B, Young J, Harpaz N, Meltzer SJ.

Gastroenterology. 1997 Jan;112(1):40-5.

PMID:
8978341
19.

Transforming growth factor beta type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer.

Akiyama Y, Iwanaga R, Saitoh K, Shiba K, Ushio K, Ikeda E, Iwama T, Nomizu T, Yuasa Y.

Gastroenterology. 1997 Jan;112(1):33-9.

PMID:
8978340
20.

Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease.

Babyatsky MW, Rossiter G, Podolsky DK.

Gastroenterology. 1996 Apr;110(4):975-84.

PMID:
8613031

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