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Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock.

Bae K, Jin X, Maywood ES, Hastings MH, Reppert SM, Weaver DR.

Neuron. 2001 May;30(2):525-36.


Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.

Zheng B, Albrecht U, Kaasik K, Sage M, Lu W, Vaishnav S, Li Q, Sun ZS, Eichele G, Bradley A, Lee CC.

Cell. 2001 Jun 1;105(5):683-94.


View of a mouse clock gene ticking.

Yamaguchi S, Kobayashi M, Mitsui S, Ishida Y, van der Horst GT, Suzuki M, Shibata S, Okamura H.

Nature. 2001 Feb 8;409(6821):684. No abstract available.


Circadian rhythm genetics: from flies to mice to humans.

Wager-Smith K, Kay SA.

Nat Genet. 2000 Sep;26(1):23-7. Review.


The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation.

Yamaguchi S, Mitsui S, Miyake S, Yan L, Onishi H, Yagita K, Suzuki M, Shibata S, Kobayashi M, Okamura H.

Curr Biol. 2000 Jul 13;10(14):873-6.


Molecular genetics of circadian rhythms in mammals.

King DP, Takahashi JS.

Annu Rev Neurosci. 2000;23:713-42. Review.


GFP fluorescence reports Period 1 circadian gene regulation in the mammalian biological clock.

Kuhlman SJ, Quintero JE, McMahon DG.

Neuroreport. 2000 May 15;11(7):1479-82.


Resetting central and peripheral circadian oscillators in transgenic rats.

Yamazaki S, Numano R, Abe M, Hida A, Takahashi R, Ueda M, Block GD, Sakaki Y, Menaker M, Tei H.

Science. 2000 Apr 28;288(5466):682-5.


Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

Lowrey PL, Shimomura K, Antoch MP, Yamazaki S, Zemenides PD, Ralph MR, Menaker M, Takahashi JS.

Science. 2000 Apr 21;288(5465):483-92.


Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms.

Field MD, Maywood ES, O'Brien JA, Weaver DR, Reppert SM, Hastings MH.

Neuron. 2000 Feb;25(2):437-47.


Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock.

Okamura H, Miyake S, Sumi Y, Yamaguchi S, Yasui A, Muijtjens M, Hoeijmakers JH, van der Horst GT.

Science. 1999 Dec 24;286(5449):2531-4.


Light-independent role of CRY1 and CRY2 in the mammalian circadian clock.

Griffin EA Jr, Staknis D, Weitz CJ.

Science. 1999 Oct 22;286(5440):768-71.


Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.

Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, Fruechte EM, Hitomi K, Thresher RJ, Ishikawa T, Miyazaki J, Takahashi JS, Sancar A.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12114-9.


mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop.

Kume K, Zylka MJ, Sriram S, Shearman LP, Weaver DR, Jin X, Maywood ES, Hastings MH, Reppert SM.

Cell. 1999 Jul 23;98(2):193-205.


Differential regulation of mPER1 and mTIM proteins in the mouse suprachiasmatic nuclei: new insights into a core clock mechanism.

Hastings MH, Field MD, Maywood ES, Weaver DR, Reppert SM.

J Neurosci. 1999 Jun 15;19(12):RC11.


A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock.

Jin X, Shearman LP, Weaver DR, Zylka MJ, de Vries GJ, Reppert SM.

Cell. 1999 Jan 8;96(1):57-68.


Molecular bases for circadian clocks.

Dunlap JC.

Cell. 1999 Jan 22;96(2):271-90. Review. No abstract available.


Inhibition of light- or glutamate-induced mPer1 expression represses the phase shifts into the mouse circadian locomotor and suprachiasmatic firing rhythms.

Akiyama M, Kouzu Y, Takahashi S, Wakamatsu H, Moriya T, Maetani M, Watanabe S, Tei H, Sakaki Y, Shibata S.

J Neurosci. 1999 Feb 1;19(3):1115-21.


Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

Sangoram AM, Saez L, Antoch MP, Gekakis N, Staknis D, Whiteley A, Fruechte EM, Vitaterna MH, Shimomura K, King DP, Young MW, Weitz CJ, Takahashi JS.

Neuron. 1998 Nov;21(5):1101-13.


The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila.

Stanewsky R, Kaneko M, Emery P, Beretta B, Wager-Smith K, Kay SA, Rosbash M, Hall JC.

Cell. 1998 Nov 25;95(5):681-92.

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