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Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation.

Kamynina E, Tauxe C, Staub O.

Am J Physiol Renal Physiol. 2001 Sep;281(3):F469-77.


Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4.

Snyder PM, Olson DR, McDonald FJ, Bucher DB.

J Biol Chem. 2001 Jul 27;276(30):28321-6. Epub 2001 May 18.


In vitro phosphorylation of COOH termini of the epithelial Na(+) channel and its effects on channel activity in Xenopus oocytes.

Chigaev A, Lu G, Shi H, Asher C, Xu R, Latter H, Seger R, Garty H, Reuveny E.

Am J Physiol Renal Physiol. 2001 Jun;280(6):F1030-6.


Solution structure of a Nedd4 WW domain-ENaC peptide complex.

Kanelis V, Rotin D, Forman-Kay JD.

Nat Struct Biol. 2001 May;8(5):407-12.


Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.

Loffing J, Zecevic M, Féraille E, Kaissling B, Asher C, Rossier BC, Firestone GL, Pearce D, Verrey F.

Am J Physiol Renal Physiol. 2001 Apr;280(4):F675-82.


The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

Harvey KF, Dinudom A, Cook DI, Kumar S.

J Biol Chem. 2001 Mar 16;276(11):8597-601. Epub 2001 Jan 17.


Two sporadic cases of Liddle's syndrome caused by De novo ENaC mutations.

Yamashita Y, Koga M, Takeda Y, Enomoto N, Uchida S, Hashimoto K, Yamano S, Dohi K, Marumo F, Sasaki S.

Am J Kidney Dis. 2001 Mar;37(3):499-504.


SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport.

Wang J, Barbry P, Maiyar AC, Rozansky DJ, Bhargava A, Leong M, Firestone GL, Pearce D.

Am J Physiol Renal Physiol. 2001 Feb;280(2):F303-13.


A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.

Kamynina E, Debonneville C, Bens M, Vandewalle A, Staub O.

FASEB J. 2001 Jan;15(1):204-214.


An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.

Schwake M, Friedrich T, Jentsch TJ.

J Biol Chem. 2001 Apr 13;276(15):12049-54. Epub 2000 Dec 14.


Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases.

Rotin D, Staub O, Haguenauer-Tsapis R.

J Membr Biol. 2000 Jul 1;176(1):1-17. Review.


Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel.

Shigaev A, Asher C, Latter H, Garty H, Reuveny E.

Am J Physiol Renal Physiol. 2000 Apr;278(4):F613-9.


Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4.

Abriel H, Kamynina E, Horisberger JD, Staub O.

FEBS Lett. 2000 Jan 28;466(2-3):377-80.


Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits.

Farr TJ, Coddington-Lawson SJ, Snyder PM, McDonald FJ.

Biochem J. 2000 Feb 1;345 Pt 3:503-9.


The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

Alvarez de la Rosa D, Zhang P, Náray-Fejes-Tóth A, Fejes-Tóth G, Canessa CM.

J Biol Chem. 1999 Dec 31;274(53):37834-9.


Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption.

Blazer-Yost BL, Păunescu TG, Helman SI, Lee KD, Vlahos CJ.

Am J Physiol. 1999 Sep;277(3 Pt 1):C531-6.


sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels.

Náray-Fejes-Tóth A, Canessa C, Cleaveland ES, Aldrich G, Fejes-Tóth G.

J Biol Chem. 1999 Jun 11;274(24):16973-8.


Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.

Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA.

EMBO J. 1999 Jun 1;18(11):3024-33.

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