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Items: 1 to 20 of 36

1.

A statistical framework for quantitative trait mapping.

Sen S, Churchill GA.

Genetics. 2001 Sep;159(1):371-87.

2.

A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice.

Poltorak A, Merlin T, Nielsen PJ, Sandra O, Smirnova I, Schupp I, Boehm T, Galanos C, Freudenberg MA.

J Immunol. 2001 Aug 15;167(4):2106-11.

3.

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.

Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nuñez G, Cho JH.

Nature. 2001 May 31;411(6837):603-6.

4.
5.

Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci.

Sugiyama F, Churchill GA, Higgins DC, Johns C, Makaritsis KP, Gavras H, Paigen B.

Genomics. 2001 Jan 1;71(1):70-7.

PMID:
11161799
6.

Heritable susceptibility for colitis in mice induced by IL-10 deficiency.

Bristol IJ, Farmer MA, Cong Y, Zheng XX, Strom TB, Elson CO, Sundberg JP, Leiter EH.

Inflamm Bowel Dis. 2000 Nov;6(4):290-302.

PMID:
11149562
7.

Qa-2-dependent selection of CD8alpha/alpha T cell receptor alpha/beta(+) cells in murine intestinal intraepithelial lymphocytes.

Das G, Gould DS, Augustine MM, Fragoso G, Sciutto E, Stroynowski I, Van Kaer L, Schust DJ, Ploegh H, Janeway CA Jr.

J Exp Med. 2000 Nov 20;192(10):1521-8. Erratum in: J Exp Med 2001 Feb 5;193(3):following 411. Scitto E [corrected to Sciutto E].

8.

The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64.

Cormier RT, Bilger A, Lillich AJ, Halberg RB, Hong KH, Gould KA, Borenstein N, Lander ES, Dove WF.

Oncogene. 2000 Jun 29;19(28):3182-92.

9.

Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci.

Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, McLeod RS, Griffiths AM, Green T, Brettin TS, Stone V, Bull SB, Bitton A, Williams CN, Greenberg GR, Cohen Z, Lander ES, Hudson TJ, Siminovitch KA.

Am J Hum Genet. 2000 Jun;66(6):1863-70. Epub 2000 Apr 21.

10.

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.

Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F.

J Exp Med. 1999 Oct 4;190(7):995-1004.

11.

Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis.

Engle SJ, Hoying JB, Boivin GP, Ormsby I, Gartside PS, Doetschman T.

Cancer Res. 1999 Jul 15;59(14):3379-86.

12.

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.

Hampe J, Schreiber S, Shaw SH, Lau KF, Bridger S, Macpherson AJ, Cardon LR, Sakul H, Harris TJ, Buckler A, Hall J, Stokkers P, van Deventer SJ, Nürnberg P, Mirza MM, Lee JC, Lennard-Jones JE, Mathew CG, Curran ME.

Am J Hum Genet. 1999 Mar;64(3):808-16.

13.

Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice.

Mähler M, Bristol IJ, Sundberg JP, Churchill GA, Birkenmeier EH, Elson CO, Leiter EH.

Genomics. 1999 Jan 15;55(2):147-56.

PMID:
9933561
14.

Experimental models to study molecular mechanisms underlying intestinal inflammation.

Elson CO, Cong Y, Brandwein S, Weaver CT, McCabe RP, Mähler M, Sundberg JP, Leiter EH.

Ann N Y Acad Sci. 1998 Nov 17;859:85-95. Review.

PMID:
9928372
15.

Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.

Cho JH, Nicolae DL, Gold LH, Fields CT, LaBuda MC, Rohal PM, Pickles MR, Qin L, Fu Y, Mann JS, Kirschner BS, Jabs EW, Weber J, Hanauer SB, Bayless TM, Brant SR.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7502-7.

16.

Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.

Mähler M, Bristol IJ, Leiter EH, Workman AE, Birkenmeier EH, Elson CO, Sundberg JP.

Am J Physiol. 1998 Mar;274(3 Pt 1):G544-51.

17.

CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease.

Cong Y, Brandwein SL, McCabe RP, Lazenby A, Birkenmeier EH, Sundberg JP, Elson CO.

J Exp Med. 1998 Mar 16;187(6):855-64.

18.

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis.

Cormier RT, Hong KH, Halberg RB, Hawkins TL, Richardson P, Mulherkar R, Dove WF, Lander ES.

Nat Genet. 1997 Sep;17(1):88-91.

PMID:
9288104
19.

Evidence for genetic heterogeneity in inflammatory bowel disease (IBD); HLA genes in the predisposition to suffer from ulcerative colitis (UC) and Crohn's disease (CD).

Bouma G, Oudkerk Pool M, Crusius JB, Schreuder GM, Hellemans HP, Meijer BU, Kostense PJ, Giphart MJ, Meuwissen SG, Peña AS.

Clin Exp Immunol. 1997 Jul;109(1):175-9.

20.

The genetics of inflammatory bowel disease.

Satsangi J, Jewell DP, Bell JI.

Gut. 1997 May;40(5):572-4. No abstract available.

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