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Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

Ellmeier W, Jung S, Sunshine MJ, Hatam F, Xu Y, Baltimore D, Mano H, Littman DR.

J Exp Med. 2000 Dec 4;192(11):1611-24.


Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex.

Guo B, Kato RM, Garcia-Lloret M, Wahl MI, Rawlings DJ.

Immunity. 2000 Aug;13(2):243-53.


Xid-like phenotypes: a B cell signalosome takes shape.

Fruman DA, Satterthwaite AB, Witte ON.

Immunity. 2000 Jul;13(1):1-3. Review. No abstract available.


Tec kinases: a family with multiple roles in immunity.

Yang WC, Collette Y, Nunès JA, Olive D.

Immunity. 2000 Apr;12(4):373-82. Review. No abstract available.


Cell-type specific phosphorylation of threonines T654 and T669 by PKD defines the signal capacity of the EGF receptor.

Bagowski CP, Stein-Gerlach M, Choidas A, Ullrich A.

EMBO J. 1999 Oct 15;18(20):5567-76.


Genetic analysis of B cell antigen receptor signaling.

Kurosaki T.

Annu Rev Immunol. 1999;17:555-92. Review.


Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.

Baraldi E, Djinovic Carugo K, Hyvönen M, Surdo PL, Riley AM, Potter BV, O'Brien R, Ladbury JE, Saraste M.

Structure. 1999 Apr 15;7(4):449-60.


In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies.

Nisitani S, Kato RM, Rawlings DJ, Witte ON, Wahl MI.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2221-6.


Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.

Dingjan GM, Maas A, Nawijn MC, Smit L, Voerman JS, Grosveld F, Hendriks RW.

EMBO J. 1998 Sep 15;17(18):5309-20.


PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals.

Scharenberg AM, Kinet JP.

Cell. 1998 Jul 10;94(1):5-8. Review. No abstract available.


SHIP modulates immune receptor responses by regulating membrane association of Btk.

Bolland S, Pearse RN, Kurosaki T, Ravetch JV.

Immunity. 1998 Apr;8(4):509-16.


Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production.

Hata D, Kawakami Y, Inagaki N, Lantz CS, Kitamura T, Khan WN, Maeda-Yamamoto M, Miura T, Han W, Hartman SE, Yao L, Nagai H, Goldfeld AE, Alt FW, Galli SJ, Witte ON, Kawakami T.

J Exp Med. 1998 Apr 20;187(8):1235-47.


Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation.

Fluckiger AC, Li Z, Kato RM, Wahl MI, Ochs HD, Longnecker R, Kinet JP, Witte ON, Scharenberg AM, Rawlings DJ.

EMBO J. 1998 Apr 1;17(7):1973-85.


Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals.

Scharenberg AM, El-Hillal O, Fruman DA, Beitz LO, Li Z, Lin S, Gout I, Cantley LC, Rawlings DJ, Kinet JP.

EMBO J. 1998 Apr 1;17(7):1961-72.


Co-receptor and accessory regulation of B-cell antigen receptor signal transduction.

Buhl AM, Cambier JC.

Immunol Rev. 1997 Dec;160:127-38. Review.


Btk dosage determines sensitivity to B cell antigen receptor cross-linking.

Satterthwaite AB, Cheroutre H, Khan WN, Sideras P, Witte ON.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13152-7.


Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptors.

Wahl MI, Fluckiger AC, Kato RM, Park H, Witte ON, Rawlings DJ.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11526-33.

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