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Items: 1 to 20 of 61


NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia.

Guttridge DC, Mayo MW, Madrid LV, Wang CY, Baldwin AS Jr.

Science. 2000 Sep 29;289(5488):2363-6.


A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.

Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.

Cancer Res. 2000 Jul 1;60(13):3504-13.


The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes.

Nakashima N, Sharma PM, Imamura T, Bookstein R, Olefsky JM.

J Biol Chem. 2000 Apr 28;275(17):12889-95.


Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation.

Guo DQ, Wu LW, Dunbar JD, Ozes ON, Mayo LD, Kessler KM, Gustin JA, Baerwald MR, Jaffe EA, Warren RS, Donner DB.

J Biol Chem. 2000 Apr 14;275(15):11216-21.


Cellular survival: a play in three Akts.

Datta SR, Brunet A, Greenberg ME.

Genes Dev. 1999 Nov 15;13(22):2905-27. Review. No abstract available.


A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes.

Hill MM, Clark SF, Tucker DF, Birnbaum MJ, James DE, Macaulay SL.

Mol Cell Biol. 1999 Nov;19(11):7771-81.


Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.

Paz K, Liu YF, Shorer H, Hemi R, LeRoith D, Quan M, Kanety H, Seger R, Zick Y.

J Biol Chem. 1999 Oct 1;274(40):28816-22.


NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase.

Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB.

Nature. 1999 Sep 2;401(6748):82-5.


Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts.

Wang Q, Somwar R, Bilan PJ, Liu Z, Jin J, Woodgett JR, Klip A.

Mol Cell Biol. 1999 Jun;19(6):4008-18.


TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells.

del Aguila LF, Claffey KP, Kirwan JP.

Am J Physiol. 1999 May;276(5 Pt 1):E849-55.


Insulin signal transduction: possible mechanisms for insulin resistance.

Kellerer M, Lammers R, Häring HU.

Exp Clin Endocrinol Diabetes. 1999;107(2):97-106. Review. No abstract available.


Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance.

Egawa K, Sharma PM, Nakashima N, Huang Y, Huver E, Boss GR, Olefsky JM.

J Biol Chem. 1999 May 14;274(20):14306-14.


PTEN: a tumour suppressor that functions as a phospholipid phosphatase.

Maehama T, Dixon JE.

Trends Cell Biol. 1999 Apr;9(4):125-8. Review.


Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein.

Peterson RT, Desai BN, Hardwick JS, Schreiber SL.

Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4438-42.


Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance.

Virkamäki A, Ueki K, Kahn CR.

J Clin Invest. 1999 Apr;103(7):931-43. Review. No abstract available.


NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation.

Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr.

Science. 1998 Sep 11;281(5383):1680-3.

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