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Items: 1 to 20 of 32

1.

The structure of acyl coenzyme A-cholesterol acyltransferase and its potential relevance to atherosclerosis.

Chang TY, Chang CC, Cadigan KM.

Trends Cardiovasc Med. 1994 Sep-Oct;4(5):223-30. doi: 10.1016/1050-1738(94)90038-8.

PMID:
21244871
2.

Free cholesterol-induced cytotoxicity a possible contributing factor to macrophage foam cell necrosis in advanced atherosclerotic lesions.

Tabas I.

Trends Cardiovasc Med. 1997 Oct;7(7):256-63. doi: 10.1016/S1050-1738(97)00086-8.

PMID:
21235894
3.

Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages.

Miyazaki A, Sakashita N, Lee O, Takahashi K, Horiuchi S, Hakamata H, Morganelli PM, Chang CC, Chang TY.

Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1568-74.

4.

Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.

Oelkers P, Behari A, Cromley D, Billheimer JT, Sturley SL.

J Biol Chem. 1998 Oct 9;273(41):26765-71.

5.

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.

Cases S, Novak S, Zheng YW, Myers HM, Lear SR, Sande E, Welch CB, Lusis AJ, Spencer TA, Krause BR, Erickson SK, Farese RV Jr.

J Biol Chem. 1998 Oct 9;273(41):26755-64.

6.

Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates.

Anderson RA, Joyce C, Davis M, Reagan JW, Clark M, Shelness GS, Rudel LL.

J Biol Chem. 1998 Oct 9;273(41):26747-54.

8.

The ACAT inhibitor, CI-1011 is effective in the prevention and regression of aortic fatty streak area in hamsters.

Nicolosi RJ, Wilson TA, Krause BR.

Atherosclerosis. 1998 Mar;137(1):77-85.

PMID:
9568739
9.

HL-004, the ACAT inhibitor, prevents the progression of atherosclerosis in cholesterol-fed rabbits.

Asami Y, Yamagishi I, Murakami S, Araki H, Tsuchida K, Higuchi S.

Life Sci. 1998;62(12):1055-63.

PMID:
9519807
10.

Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death.

Kellner-Weibel G, Jerome WG, Small DM, Warner GJ, Stoltenborg JK, Kearney MA, Corjay MH, Phillips MC, Rothblat GH.

Arterioscler Thromb Vasc Biol. 1998 Mar;18(3):423-31.

11.

Tissue expression studies on the mouse acyl-CoA: cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice.

Meiner V, Tam C, Gunn MD, Dong LM, Weisgraber KH, Novak S, Myers HM, Erickson SK, Farese RV Jr.

J Lipid Res. 1997 Sep;38(9):1928-33.

12.

Acyl-coenzyme A:cholesterol acyltransferase.

Chang TY, Chang CC, Cheng D.

Annu Rev Biochem. 1997;66:613-38. Review.

PMID:
9242919
13.
14.

Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets.

Lee HT, Sliskovic DR, Picard JA, Roth BD, Wierenga W, Hicks JL, Bousley RF, Hamelehle KL, Homan R, Speyer C, Stanfield RL, Krause BR.

J Med Chem. 1996 Dec 20;39(26):5031-4. No abstract available.

PMID:
8978833
15.

Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals.

Meiner VL, Cases S, Myers HM, Sande ER, Bellosta S, Schambelan M, Pitas RE, McGuire J, Herz J, Farese RV Jr.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14041-6.

16.

Macrophages and atherosclerotic plaque stability.

Libby P, Geng YJ, Aikawa M, Schoenbeck U, Mach F, Clinton SK, Sukhova GK, Lee RT.

Curr Opin Lipidol. 1996 Oct;7(5):330-5. Review.

PMID:
8937525
17.
18.

Effect of FR145237, a novel ACAT inhibitor, on atherogenesis in cholesterol-fed and WHHL rabbits. Evidence for a direct effect on the arterial wall.

Matsuo M, Ito F, Konto A, Aketa M, Tomoi M, Shimomura K.

Biochim Biophys Acta. 1995 Dec 7;1259(3):254-60.

PMID:
8541332
19.
20.

The spectrum of normolipemic plane xanthoma.

Williford PM, White WL, Jorizzo JL, Greer K.

Am J Dermatopathol. 1993 Dec;15(6):572-5.

PMID:
8311190

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