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Items: 1 to 20 of 54


GEFs: structural basis for their activation of small GTP-binding proteins.

Cherfils J, Chardin P.

Trends Biochem Sci. 1999 Aug;24(8):306-11. Review.


Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

Anborgh PH, Qian X, Papageorge AG, Vass WC, DeClue JE, Lowy DR.

Mol Cell Biol. 1999 Jul;19(7):4611-22.


G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm).

Kiyono M, Satoh T, Kaziro Y.

Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4826-31.


Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation.

Cheng AM, Saxton TM, Sakai R, Kulkarni S, Mbamalu G, Vogel W, Tortorice CG, Cardiff RD, Cross JC, Muller WJ, Pawson T.

Cell. 1998 Dec 11;95(6):793-803.


Regulation of RasGRP via a phorbol ester-responsive C1 domain.

Tognon CE, Kirk HE, Passmore LA, Whitehead IP, Der CJ, Kay RJ.

Mol Cell Biol. 1998 Dec;18(12):6995-7008.


Increasing complexity of Ras signaling.

Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ.

Oncogene. 1998 Sep 17;17(11 Reviews):1395-413. Review.


Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway.

Wasylyk B, Hagman J, Gutierrez-Hartmann A.

Trends Biochem Sci. 1998 Jun;23(6):213-6. Review.


Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.

Oldham SM, Cox AD, Reynolds ER, Sizemore NS, Coffey RJ Jr, Der CJ.

Oncogene. 1998 May;16(20):2565-73.


RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs.

Ebinu JO, Bottorff DA, Chan EY, Stang SL, Dunn RJ, Stone JC.

Science. 1998 May 15;280(5366):1082-6.


Defective trophoblast function in mice with a targeted mutation of Ets2.

Yamamoto H, Flannery ML, Kupriyanov S, Pearce J, McKercher SR, Henkel GW, Maki RA, Werb Z, Oshima RG.

Genes Dev. 1998 May 1;12(9):1315-26.


N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains.

Qian X, Vass WC, Papageorge AG, Anborgh PH, Lowy DR.

Mol Cell Biol. 1998 Feb;18(2):771-8.


Mash2 acts cell autonomously in mouse spongiotrophoblast development.

Tanaka M, Gertsenstein M, Rossant J, Nagy A.

Dev Biol. 1997 Oct 1;190(1):55-65.


Molecular genetics of implantation in the mouse.

Rinkenberger JL, Cross JC, Werb Z.

Dev Genet. 1997;21(1):6-20. Review.


Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice.

Gnarra JR, Ward JM, Porter FD, Wagner JR, Devor DE, Grinberg A, Emmert-Buck MR, Westphal H, Klausner RD, Linehan WM.

Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9102-7.


A 54-kDa protein related to ras-guanine nucleotide release factor expressed in the rat exocrine pancreas.

Tung PS, Fam NP, Chen L, Moran MF.

Cell Tissue Res. 1997 Sep;289(3):505-15.


Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.

McCarthy SA, Chen D, Yang BS, Garcia Ramirez JJ, Cherwinski H, Chen XR, Klagsbrun M, Hauser CA, Ostrowski MC, McMahon M.

Mol Cell Biol. 1997 May;17(5):2401-12.


Ras-independent transformation by v-Src.

Aftab DT, Kwan J, Martin GS.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3028-33.


Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras.

Fam NP, Fan WT, Wang Z, Zhang LJ, Chen H, Moran MF.

Mol Cell Biol. 1997 Mar;17(3):1396-406.


Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development.

Wang DZ, Hammond VE, Abud HE, Bertoncello I, McAvoy JW, Bowtell DD.

Genes Dev. 1997 Feb 1;11(3):309-20.

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