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Items: 1 to 20 of 25


Aggregation risk prediction for antibodies and its application to biotherapeutic development.

Obrezanova O, Arnell A, de la Cuesta RG, Berthelot ME, Gallagher TR, Zurdo J, Stallwood Y.

MAbs. 2015;7(2):352-63. doi: 10.1080/19420862.2015.1007828.


Exploring peptide mimics for the production of antibodies against discontinuous protein epitopes.

Irving MB, Craig L, Menendez A, Gangadhar BP, Montero M, van Houten NE, Scott JK.

Mol Immunol. 2010 Feb;47(5):1137-48. doi: 10.1016/j.molimm.2009.10.015. Epub 2009 Dec 23.


Biomolecule association rates do not provide a complete description of bond formation.

Robert P, Limozin L, Pierres A, Bongrand P.

Biophys J. 2009 Jun 3;96(11):4642-50. doi: 10.1016/j.bpj.2009.03.020.


Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments.

Richman SA, Aggen DH, Dossett ML, Donermeyer DL, Allen PM, Greenberg PD, Kranz DM.

Mol Immunol. 2009 Feb;46(5):902-16. doi: 10.1016/j.molimm.2008.09.021. Epub 2008 Oct 29.


Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.

Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA.

J Mol Biol. 2007 Jun 8;369(3):696-709. Epub 2007 Jan 27.


A structurally based approach to determine HLA compatibility at the humoral immune level.

Duquesnoy RJ.

Hum Immunol. 2006 Nov;67(11):847-62. Epub 2006 Sep 1.


Exploring protein interfaces with a general photochemical reagent.

Gómez GE, Cauerhff A, Craig PO, Goldbaum FA, Delfino JM.

Protein Sci. 2006 Apr;15(4):744-52.


CEP: a conformational epitope prediction server.

Kulkarni-Kale U, Bhosle S, Kolaskar AS.

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W168-71.


Structural mechanism for affinity maturation of an anti-lysozyme antibody.

Cauerhff A, Goldbaum FA, Braden BC.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3539-44. Epub 2004 Feb 26.


Interaction between the antigen and antibody is controlled by the constant domains: normal mode dynamics of the HEL-HyHEL-10 complex.

Adachi M, Kurihara Y, Nojima H, Takeda-Shitaka M, Kamiya K, Umeyama H.

Protein Sci. 2003 Oct;12(10):2125-31.


Interactions of protein antigens with antibodies.

Davies DR, Cohen GH.

Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):7-12. Review.


Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Chitarra V, Alzari PM, Bentley GA, Bhat TN, Eiselé JL, Houdusse A, Lescar J, Souchon H, Poljak RJ.

Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7711-5.

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