Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 116


Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD, Wang HG, Reed JC, Nicholson DW, Alnemri ES, Green DR, Martin SJ.

J Cell Biol. 1999 Jan 25;144(2):281-92.


The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis.

Lauber K, Appel HA, Schlosser SF, Gregor M, Schulze-Osthoff K, Wesselborg S.

J Biol Chem. 2001 Aug 10;276(32):29772-81. Epub 2001 May 31.


Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.

Pandey P, Saleh A, Nakazawa A, Kumar S, Srinivasula SM, Kumar V, Weichselbaum R, Nalin C, Alnemri ES, Kufe D, Kharbanda S.

EMBO J. 2000 Aug 15;19(16):4310-22.


Activation of caspases triggered by cytochrome c in vitro.

Pan G, Humke EW, Dixit VM.

FEBS Lett. 1998 Apr 10;426(1):151-4. Erratum in: FEBS Lett 1998 May 29;428(3):309.


Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X.

Cell. 1997 Nov 14;91(4):479-89.


Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity.

Wolf BB, Schuler M, Li W, Eggers-Sedlet B, Lee W, Tailor P, Fitzgerald P, Mills GB, Green DR.

J Biol Chem. 2001 Sep 7;276(36):34244-51. Epub 2001 Jun 27.


IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.

Deveraux QL, Roy N, Stennicke HR, Van Arsdale T, Zhou Q, Srinivasula SM, Alnemri ES, Salvesen GS, Reed JC.

EMBO J. 1998 Apr 15;17(8):2215-23.


Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.

Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Alnemri ES.

Mol Cell. 1998 Jun;1(7):949-57.


Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.

Twiddy D, Brown DG, Adrain C, Jukes R, Martin SJ, Cohen GM, MacFarlane M, Cain K.

J Biol Chem. 2004 May 7;279(19):19665-82. Epub 2004 Mar 1.


Caspase-8 in apoptosis: the beginning of "the end"?

Kruidering M, Evan GI.

IUBMB Life. 2000 Aug;50(2):85-90. Review.


Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome.

Marsden VS, O'Connor L, O'Reilly LA, Silke J, Metcalf D, Ekert PG, Huang DC, Cecconi F, Kuida K, Tomaselli KJ, Roy S, Nicholson DW, Vaux DL, Bouillet P, Adams JM, Strasser A.

Nature. 2002 Oct 10;419(6907):634-7. Epub 2002 Sep 25.


Caspases induce cytochrome c release from mitochondria by activating cytosolic factors.

Bossy-Wetzel E, Green DR.

J Biol Chem. 1999 Jun 18;274(25):17484-90.


Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis.

Gao CF, Ren S, Zhang L, Nakajima T, Ichinose S, Hara T, Koike K, Tsuchida N.

Exp Cell Res. 2001 Apr 15;265(1):145-51.


A novel Apaf-1-independent putative caspase-2 activation complex.

Read SH, Baliga BC, Ekert PG, Vaux DL, Kumar S.

J Cell Biol. 2002 Dec 9;159(5):739-45. Epub 2002 Dec 2.

Supplemental Content

Support Center