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Items: 1 to 20 of 84

1.

Structure activity relationship study of known inhibitors of the enzyme 5 alpha-reductase (5AR).

Ahmed S, Denison S.

Bioorg Med Chem Lett. 1998 Mar 3;8(5):409-14.

PMID:
9871588
2.

Mechanism based representation of the active site of 5 alpha-reductase (5AR).

Ahmed S, Denison S.

Bioorg Med Chem Lett. 1998 Sep 22;8(18):2615-70.

PMID:
9873591
3.

Efficient construction of 6-azasteroids: dual inhibitors of steroidal 5 alpha-reductase.

Sharp MJ, Fang FG.

Bioorg Med Chem Lett. 1998 Dec 1;8(23):3291-4.

PMID:
9873720
4.

Comparative pharmacophore development for inhibitors of human and rat 5-alpha-reductase.

Faragalla J, Bremner J, Brown D, Griffith R, Heaton A.

J Mol Graph Model. 2003 Sep;22(1):83-92.

PMID:
12798393
5.

Structure-activity relationship study of steroidal and nonsteroidal inhibitors of the enzyme estrone sulfatase.

Ahmed S, James K, Sampson L, Mastri C.

Biochem Biophys Res Commun. 1999 Jan 27;254(3):811-5.

PMID:
9920822
6.

Synthesis of benzanilide derivatives as dual acting agents with alpha 1-adrenoceptor antagonistic action and steroid 5-alpha reductase inhibitory activity.

Yoshida K, Horikoshi Y, Eta M, Chikazawa J, Ogishima M, Fukuda Y, Sato H.

Bioorg Med Chem Lett. 1998 Nov 3;8(21):2967-72.

PMID:
9873656
7.

Novel C-6 substituted and unsubstituted pregnane derivatives as 5alpha-reductase inhibitors and their effect on hamster flank organs diameter size.

Cabeza M, Zambrano A, Heuze I, Carrizales E, Palacios A, Segura T, Valencia N, Bratoeff E.

Steroids. 2009 Oct;74(10-11):793-802. doi: 10.1016/j.steroids.2009.04.009. Epub 2009 May 4.

PMID:
19406144
8.

Substrate interaction with 5alpha-reductase enzyme: influence of the 17beta-chain chirality in the mechanism of action of 4-azasteroid inhibitors.

Grisenti P, Magni A, Olgiati V, Manzocchi A, Ferraboschi P, Villani V, Pucciariello R, Celotti F.

Steroids. 2001 Nov;66(11):803-10.

PMID:
11576619
10.
11.

Recent advances in the chemistry and pharmacological activity of new steroidal antiandrogens and 5 alpha-reductase inhibitors.

Bratoeff E, Cabeza M, Ramirez E, Heuze Y, Flores E.

Curr Med Chem. 2005;12(8):927-43. Review.

PMID:
15853706
12.

Synthesis and 5 alpha-reductase inhibitory activity of 8-substituted benzo[f]quinolinones derived from palladium mediated coupling reactions.

Smith EC, McQuaid LA, Goode RL, McNulty AM, Neubauer BL, Rocco VP, Audia JE.

Bioorg Med Chem Lett. 1998 Feb 17;8(4):395-8.

PMID:
9871692
13.

Biphenyls as surrogates of the steroidal backbone. Part 2: discovery of a novel family of non-steroidal 5-alpha-reductase inhibitors.

Lesuisse D, Gourvest JF, Albert E, Doucet B, Hartmann C, Lefrançois JM, Tessier S, Tric B, Teutsch G.

Bioorg Med Chem Lett. 2001 Jul 9;11(13):1713-6.

PMID:
11425544
14.
15.

The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles.

Niiyama S, Kojima K, Hamada T, Happle R, Hoffmann R.

Eur J Dermatol. 2000 Dec;10(8):593-5.

PMID:
11125319
16.

Structure-activity relationships and molecular modelling of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors.

Maccari R, Ottanà R, Curinga C, Vigorita MG, Rakowitz D, Steindl T, Langer T.

Bioorg Med Chem. 2005 Apr 15;13(8):2809-23.

PMID:
15781392
17.

Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5 alpha-reductase 1.

Guarna A, Occhiato EG, Machetti F, Trabocchi A, Scarpi D, Danza G, Mancina R, Comerci A, Serio M.

Bioorg Med Chem. 2001 Jun;9(6):1385-93.

PMID:
11408159
18.

[Enzyme inhibition in the drug therapy of benign prostatic hyperplasia].

Drsata J.

Cas Lek Cesk. 2002 Oct 11;141(20):630-5. Review. Czech.

PMID:
12515038
19.

Evaluation of 4'-substituted bicyclic pyridones as non-steroidal inhibitors of steroid 5alpha-reductase.

McCarthy AR, Hartmann RW, Abell AD.

Bioorg Med Chem Lett. 2007 Jul 1;17(13):3603-7. Epub 2007 Apr 24.

PMID:
17490876
20.

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