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Items: 1 to 20 of 186

1.

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor.

Tsukazaki T, Chiang TA, Davison AF, Attisano L, Wrana JL.

Cell. 1998 Dec 11;95(6):779-91.

2.

Structural basis of Smad2 recognition by the Smad anchor for receptor activation.

Wu G, Chen YG, Ozdamar B, Gyuricza CA, Chong PA, Wrana JL, Massagué J, Shi Y.

Science. 2000 Jan 7;287(5450):92-7.

3.

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling.

Itoh F, Divecha N, Brocks L, Oomen L, Janssen H, Calafat J, Itoh S, Dijke Pt Pt.

Genes Cells. 2002 Mar;7(3):321-31.

4.

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling.

Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, Grinnell BW, Richardson MA, Topper JN, Gimbrone MA Jr, Wrana JL, Falb D.

Cell. 1997 Jun 27;89(7):1165-73.

5.

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.

Nakao A, Imamura T, Souchelnytskyi S, Kawabata M, Ishisaki A, Oeda E, Tamaki K, Hanai J, Heldin CH, Miyazono K, ten Dijke P.

EMBO J. 1997 Sep 1;16(17):5353-62.

7.

Interaction between Smad anchor for receptor activation and Smad3 is not essential for TGF-beta/Smad3-mediated signaling.

Goto D, Nakajima H, Mori Y, Kurasawa K, Kitamura N, Iwamoto I.

Biochem Biophys Res Commun. 2001 Mar;281(5):1100-5.

PMID:
11243848
8.

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

Miura S, Takeshita T, Asao H, Kimura Y, Murata K, Sasaki Y, Hanai JI, Beppu H, Tsukazaki T, Wrana JL, Miyazono K, Sugamura K.

Mol Cell Biol. 2000 Dec;20(24):9346-55.

10.

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling.

Souchelnytskyi S, Tamaki K, Engström U, Wernstedt C, ten Dijke P, Heldin CH.

J Biol Chem. 1997 Oct 31;272(44):28107-15.

11.

A novel dominant negative Smad2 mutation in a TGFbeta resistant human carcinoma cell line.

Tsang KJ, Tsang D, Brown TN, Crowe DL.

Anticancer Res. 2002 Jan-Feb;22(1A):13-9.

PMID:
12017275
12.

PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster.

Bennett D, Alphey L.

Nat Genet. 2002 Aug;31(4):419-23. Epub 2002 Jul 22.

PMID:
12134149
13.

The Smad pathway.

Wrana JL, Attisano L.

Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):5-13. Review.

PMID:
10708948
14.

Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development.

Faure S, Lee MA, Keller T, ten Dijke P, Whitman M.

Development. 2000 Jul;127(13):2917-31.

15.
16.

Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.

Mori Y, Ishida W, Bhattacharyya S, Li Y, Platanias LC, Varga J.

Arthritis Rheum. 2004 Dec;50(12):4008-21.

19.

Endofin acts as a Smad anchor for receptor activation in BMP signaling.

Shi W, Chang C, Nie S, Xie S, Wan M, Cao X.

J Cell Sci. 2007 Apr 1;120(Pt 7):1216-24. Epub 2007 Mar 13.

20.

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling.

Abdollah S, Macías-Silva M, Tsukazaki T, Hayashi H, Attisano L, Wrana JL.

J Biol Chem. 1997 Oct 31;272(44):27678-85.

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