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Items: 1 to 20 of 93

1.

Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior.

Gogos JA, Morgan M, Luine V, Santha M, Ogawa S, Pfaff D, Karayiorgou M.

Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9991-6.

2.

Effect of dopamine uptake inhibition on brain catecholamine levels and locomotion in catechol-O-methyltransferase-disrupted mice.

Huotari M, Santha M, Lucas LR, Karayiorgou M, Gogos JA, Männistö PT.

J Pharmacol Exp Ther. 2002 Dec;303(3):1309-16.

3.

Exploratory and habituation phenotype of heterozygous and homozygous COMT knockout mice.

Babovic D, O'Tuathaigh CM, O'Sullivan GJ, Clifford JJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL.

Behav Brain Res. 2007 Nov 2;183(2):236-9. Epub 2007 Jul 12.

PMID:
17707921
4.

Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase.

Babovic D, O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL.

Neuroscience. 2008 Sep 9;155(4):1021-9. doi: 10.1016/j.neuroscience.2008.07.006. Epub 2008 Jul 10.

PMID:
18674597
5.

Tissue histopathology, clinical chemistry and behaviour of adult Comt-gene-disrupted mice.

Haasio K, Huotari M, Nissinen E, Männistö PT.

J Appl Toxicol. 2003 Jul-Aug;23(4):213-9.

PMID:
12884403
6.

Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.

Huotari M, Gogos JA, Karayiorgou M, Koponen O, Forsberg M, Raasmaja A, Hyttinen J, Männistö PT.

Eur J Neurosci. 2002 Jan;15(2):246-56.

PMID:
11849292
7.

Reduced natriuretic response to acute sodium loading in COMT gene deleted mice.

Odlind C, Reenilä I, Männistö PT, Juvonen R, Uhlén S, Gogos JA, Karayiorgou M, Hansell P.

BMC Physiol. 2002 Aug 21;2:14.

8.

Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice.

Desbonnet L, Tighe O, Karayiorgou M, Gogos JA, Waddington JL, O'Tuathaigh CM.

Behav Brain Res. 2012 Mar 17;228(2):351-8. doi: 10.1016/j.bbr.2011.12.014. Epub 2011 Dec 17.

PMID:
22192380
9.

Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum.

Yavich L, Forsberg MM, Karayiorgou M, Gogos JA, Männistö PT.

J Neurosci. 2007 Sep 19;27(38):10196-209.

10.

Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice.

Tammimäki A, Käenmäki M, Kambur O, Kulesskaya N, Keisala T, Karvonen E, García-Horsman JA, Rauvala H, Männistö PT.

Psychopharmacology (Berl). 2010 Sep;211(4):389-401. doi: 10.1007/s00213-010-1944-2. Epub 2010 Jul 9.

PMID:
20617305
11.

Sex-dependent compensated oxidative stress in the mouse liver upon deletion of catechol O-methyltransferase.

Tenorio-Laranga J, Männistö PT, Karayiorgou M, Gogos JA, García-Horsman JA.

Biochem Pharmacol. 2009 May 1;77(9):1541-52. doi: 10.1016/j.bcp.2009.02.004. Epub 2009 Feb 21.

PMID:
19426692
12.

Catecholamines and aggression: the role of COMT and MAO polymorphisms.

Volavka J, Bilder R, Nolan K.

Ann N Y Acad Sci. 2004 Dec;1036:393-8. Review.

PMID:
15817751
13.

D-amphetamine responses in catechol-O-methyltransferase (COMT) disrupted mice.

Huotari M, García-Horsman JA, Karayiorgou M, Gogos JA, Männistö PT.

Psychopharmacology (Berl). 2004 Feb;172(1):1-10. Epub 2003 Oct 23.

PMID:
14574438
14.

Increase in free choice oral ethanol self-administration in catechol-o-methyltransferase gene-disrupted male mice.

Tammimäki A, Forsberg MM, Karayiorgou M, Gogos JA, Männistö PT.

Basic Clin Pharmacol Toxicol. 2008 Oct;103(4):297-304. doi: 10.1111/j.1742-7843.2008.00267.x. Epub 2008 Jul 18.

15.

Dopamine metabolism in adults with 22q11 deletion syndrome, with and without schizophrenia--relationship with COMT Val¹⁰⁸/¹⁵⁸Met polymorphism, gender and symptomatology.

Boot E, Booij J, Abeling N, Meijer J, da Silva Alves F, Zinkstok J, Baas F, Linszen D, van Amelsvoort T.

J Psychopharmacol. 2011 Jul;25(7):888-95. doi: 10.1177/0269881111400644. Epub 2011 Mar 29.

PMID:
21447540
16.

Stress-induced analgesia and morphine responses are changed in catechol-O-methyltransferase-deficient male mice.

Kambur O, Männistö PT, Viljakka K, Reenilä I, Lemberg K, Kontinen VK, Karayiorgou M, Gogos JA, Kalso E.

Basic Clin Pharmacol Toxicol. 2008 Oct;103(4):367-73. doi: 10.1111/j.1742-7843.2008.00289.x.

17.

Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype.

Tammimaki A, Aonurm-Helm A, Zhang FP, Poutanen M, Duran-Torres G, Garcia-Horsman A, Mannisto PT.

J Physiol Pharmacol. 2016 Dec;67(6):827-842.

18.

Importance of the COMT gene for sex differences in brain function and predisposition to psychiatric disorders.

Tunbridge EM, Harrison PJ.

Curr Top Behav Neurosci. 2011;8:119-40. doi: 10.1007/7854_2010_97. Review.

PMID:
21769726
19.

Catecholamines in patients with 22q11.2 deletion syndrome and the low-activity COMT polymorphism.

Graf WD, Unis AS, Yates CM, Sulzbacher S, Dinulos MB, Jack RM, Dugaw KA, Paddock MN, Parson WW.

Neurology. 2001 Aug 14;57(3):410-6.

PMID:
11502905
20.

Estrogen deficient male mice develop compulsive behavior.

Hill RA, McInnes KJ, Gong EC, Jones ME, Simpson ER, Boon WC.

Biol Psychiatry. 2007 Feb 1;61(3):359-66. Epub 2006 Mar 29.

PMID:
16566897

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