Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 216

2.

Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.

Kirken RA, Rui H, Malabarba MG, Howard OM, Kawamura M, O'Shea JJ, Farrar WL.

Cytokine. 1995 Oct;7(7):689-700.

PMID:
8580378
3.
4.
5.
6.

IL-2 induces conformational changes in its preassembled receptor core, which then migrates in lipid raft and binds to the cytoskeleton meshwork.

Pillet AH, Lavergne V, Pasquier V, Gesbert F, Thèze J, Rose T.

J Mol Biol. 2010 Nov 12;403(5):671-92. doi: 10.1016/j.jmb.2010.08.056. Epub 2010 Sep 21.

PMID:
20816854
7.

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.

Fujii H, Nakagawa Y, Schindler U, Kawahara A, Mori H, Gouilleux F, Groner B, Ihle JN, Minami Y, Miyazaki T, et al.

Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5482-6.

8.

SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.

Cohney SJ, Sanden D, Cacalano NA, Yoshimura A, Mui A, Migone TS, Johnston JA.

Mol Cell Biol. 1999 Jul;19(7):4980-8.

9.

The interleukin-4 receptor activates STAT5 by a mechanism that relies upon common gamma-chain.

Lischke A, Moriggl R, Brändlein S, Berchtold S, Kammer W, Sebald W, Groner B, Liu X, Hennighausen L, Friedrich K.

J Biol Chem. 1998 Nov 20;273(47):31222-9.

10.

CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signaling.

Aman MJ, Migone TS, Sasaki A, Ascherman DP, Zhu Mh, Soldaini E, Imada K, Miyajima A, Yoshimura A, Leonard WJ.

J Biol Chem. 1999 Oct 15;274(42):30266-72.

11.

Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity.

Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA.

J Biol Chem. 1996 Aug 30;271(35):21381-90.

12.

Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.

Zhou YJ, Magnuson KS, Cheng TP, Gadina M, Frucht DM, Galon J, Candotti F, Geahlen RL, Changelian PS, O'Shea JJ.

Mol Cell Biol. 2000 Jun;20(12):4371-80.

13.

Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.

Hornakova T, Staerk J, Royer Y, Flex E, Tartaglia M, Constantinescu SN, Knoops L, Renauld JC.

J Biol Chem. 2009 Mar 13;284(11):6773-81. doi: 10.1074/jbc.M807531200. Epub 2009 Jan 12.

14.

Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line.

Higuchi M, Asao H, Tanaka N, Oda K, Takeshita T, Nakamura M, Van Snick J, Sugamura K.

Eur J Immunol. 1996 Jun;26(6):1322-7.

PMID:
8647212
15.

Convergence of signaling transduced by prolactin (PRL)/cytokine chimeric receptors on PRL-responsive gene transcription.

Ferrag F, Chiarenza A, Goffin V, Kelly PA.

Mol Endocrinol. 1996 Apr;10(4):451-60.

PMID:
8721989
16.

Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation.

Migone TS, Rodig S, Cacalano NA, Berg M, Schreiber RD, Leonard WJ.

Mol Cell Biol. 1998 Nov;18(11):6416-22.

17.

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits.

Miyazaki T, Kawahara A, Fujii H, Nakagawa Y, Minami Y, Liu ZJ, Oishi I, Silvennoinen O, Witthuhn BA, Ihle JN, et al.

Science. 1994 Nov 11;266(5187):1045-7.

PMID:
7973659
18.
19.
20.

Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain.

Cacalano NA, Migone TS, Bazan F, Hanson EP, Chen M, Candotti F, O'Shea JJ, Johnston JA.

EMBO J. 1999 Mar 15;18(6):1549-58.

Supplemental Content

Support Center