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Items: 1 to 20 of 419

1.

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.

Patton EE, Willems AR, Sa D, Kuras L, Thomas D, Craig KL, Tyers M.

Genes Dev. 1998 Mar 1;12(5):692-705. Erratum in: Genes Dev 1998 Oct 1;12(19):3144.

2.

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW.

Cell. 1997 Oct 17;91(2):209-19.

3.

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ.

Genes Dev. 1999 Jun 15;13(12):1614-26.

4.

Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1.

Kaiser P, Sia RA, Bardes EG, Lew DJ, Reed SI.

Genes Dev. 1998 Aug 15;12(16):2587-97.

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Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

Skowyra D, Koepp DM, Kamura T, Conrad MN, Conaway RC, Conaway JW, Elledge SJ, Harper JW.

Science. 1999 Apr 23;284(5414):662-5.

7.

SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.

Willems AR, Goh T, Taylor L, Chernushevich I, Shevchenko A, Tyers M.

Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29;354(1389):1533-50.

8.

Grr1 functions in the ubiquitin pathway in Saccharomyces cerevisiae through association with Skp1.

Kishi T, Seno T, Yamao F.

Mol Gen Genet. 1998 Jan;257(2):143-8.

PMID:
9491072
9.

Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.

Willems AR, Lanker S, Patton EE, Craig KL, Nason TF, Mathias N, Kobayashi R, Wittenberg C, Tyers M.

Cell. 1996 Aug 9;86(3):453-63.

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Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein.

Lyapina SA, Correll CC, Kipreos ET, Deshaies RJ.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7451-6.

13.

Transferable domain in the G(1) cyclin Cln2 sufficient to switch degradation of Sic1 from the E3 ubiquitin ligase SCF(Cdc4) to SCF(Grr1).

Berset C, Griac P, Tempel R, La Rue J, Wittenberg C, Lanker S.

Mol Cell Biol. 2002 Jul;22(13):4463-76.

14.

A refined two-hybrid system reveals that SCF(Cdc4)-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entry.

Kishi T, Ikeda A, Koyama N, Fukada J, Nagao R.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14497-502. doi: 10.1073/pnas.0806253105. Epub 2008 Sep 11.

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.

Bai C, Sen P, Hofmann K, Ma L, Goebl M, Harper JW, Elledge SJ.

Cell. 1996 Jul 26;86(2):263-74.

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20.

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle.

Freed E, Lacey KR, Huie P, Lyapina SA, Deshaies RJ, Stearns T, Jackson PK.

Genes Dev. 1999 Sep 1;13(17):2242-57.

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