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Items: 1 to 20 of 102

2.
3.

Structural determinants of substrate selection by the human insulin-receptor protein-tyrosine kinase.

Keane NE, Chavanieu A, Quirk PG, Evans JS, Levine BA, Calas B, Wei L, Ellis L.

Eur J Biochem. 1994 Dec 1;226(2):525-36.

4.

Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.

Wilden PA, Kahn CR, Siddle K, White MF.

J Biol Chem. 1992 Aug 15;267(23):16660-8.

5.
6.

Kinase inhibition by a phosphorylated peptide corresponding to the major insulin receptor autophosphorylation domain.

Chavanieu A, Calas B, Vaglio P, Grigorescu F.

Eur J Biochem. 1992 Sep 1;208(2):367-73.

7.

Autophosphorylation induces autoactivation and a decrease in the Src homology 2 domain accessibility of the Lyn protein kinase.

Sotirellis N, Johnson TM, Hibbs ML, Stanley IJ, Stanley E, Dunn AR, Cheng HC.

J Biol Chem. 1995 Dec 15;270(50):29773-80.

8.

Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation.

Pautsch A, Zoephel A, Ahorn H, Spevak W, Hauptmann R, Nar H.

Structure. 2001 Oct;9(10):955-65.

9.

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP.

Yang J, Cron P, Good VM, Thompson V, Hemmings BA, Barford D.

Nat Struct Biol. 2002 Dec;9(12):940-4.

PMID:
12434148
10.

Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM.

J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20.

11.

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.

Bax B, Carter PS, Lewis C, Guy AR, Bridges A, Tanner R, Pettman G, Mannix C, Culbert AA, Brown MJ, Smith DG, Reith AD.

Structure. 2001 Dec;9(12):1143-52.

12.

Crystal structure of the tyrosine kinase domain of the human insulin receptor.

Hubbard SR, Wei L, Ellis L, Hendrickson WA.

Nature. 1994 Dec 22-29;372(6508):746-54.

PMID:
7997262
13.

Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.

Hu J, Liu J, Ghirlando R, Saltiel AR, Hubbard SR.

Mol Cell. 2003 Dec;12(6):1379-89.

14.

Structure and autoregulation of the insulin-like growth factor 1 receptor kinase.

Favelyukis S, Till JH, Hubbard SR, Miller WT.

Nat Struct Biol. 2001 Dec;8(12):1058-63.

PMID:
11694888
16.

Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.

Till JH, Ablooglu AJ, Frankel M, Bishop SM, Kohanski RA, Hubbard SR.

J Biol Chem. 2001 Mar 30;276(13):10049-55. Epub 2000 Dec 21.

17.

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism.

Mohammadi M, Schlessinger J, Hubbard SR.

Cell. 1996 Aug 23;86(4):577-87.

18.

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.

Lee CC, Jia Y, Li N, Sun X, Ng K, Ambing E, Gao MY, Hua S, Chen C, Kim S, Michellys PY, Lesley SA, Harris JL, Spraggon G.

Biochem J. 2010 Sep 15;430(3):425-37. doi: 10.1042/BJ20100609.

PMID:
20632993
19.

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.

Wybenga-Groot LE, Baskin B, Ong SH, Tong J, Pawson T, Sicheri F.

Cell. 2001 Sep 21;106(6):745-57.

20.

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