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Items: 1 to 20 of 181

1.

Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.

Zabner J, Cheng SH, Meeker D, Launspach J, Balfour R, Perricone MA, Morris JE, Marshall J, Fasbender A, Smith AE, Welsh MJ.

J Clin Invest. 1997 Sep 15;100(6):1529-37.

2.

Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis.

Hyde SC, Southern KW, Gileadi U, Fitzjohn EM, Mofford KA, Waddell BE, Gooi HC, Goddard CA, Hannavy K, Smyth SE, Egan JJ, Sorgi FL, Huang L, Cuthbert AW, Evans MJ, Colledge WH, Higgins CF, Webb AK, Gill DR.

Gene Ther. 2000 Jul;7(13):1156-65.

3.

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

Zabner J, Couture LA, Gregory RJ, Graham SM, Smith AE, Welsh MJ.

Cell. 1993 Oct 22;75(2):207-16.

PMID:
7691415
4.

A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis.

Gill DR, Southern KW, Mofford KA, Seddon T, Huang L, Sorgi F, Thomson A, MacVinish LJ, Ratcliff R, Bilton D, Lane DJ, Littlewood JM, Webb AK, Middleton PG, Colledge WH, Cuthbert AW, Evans MJ, Higgins CF, Hyde SC.

Gene Ther. 1997 Mar;4(3):199-209.

5.

Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis.

Noone PG, Hohneker KW, Zhou Z, Johnson LG, Foy C, Gipson C, Jones K, Noah TL, Leigh MW, Schwartzbach C, Efthimiou J, Pearlman R, Boucher RC, Knowles MR.

Mol Ther. 2000 Jan;1(1):105-14.

6.

Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.

Wagner JA, Messner AH, Moran ML, Daifuku R, Kouyama K, Desch JK, Manley S, Norbash AM, Conrad CK, Friborg S, Reynolds T, Guggino WB, Moss RB, Carter BJ, Wine JJ, Flotte TR, Gardner P.

Laryngoscope. 1999 Feb;109(2 Pt 1):266-74.

PMID:
10890777
7.

Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis.

Zabner J, Ramsey BW, Meeker DP, Aitken ML, Balfour RP, Gibson RL, Launspach J, Moscicki RA, Richards SM, Standaert TA, et al.

J Clin Invest. 1996 Mar 15;97(6):1504-11.

8.

Cationic lipid:pDNA complexes for the treatment of cystic fibrosis.

Eastman SJ, Scheule RK.

Curr Opin Mol Ther. 1999 Apr;1(2):186-96. Review.

PMID:
11715942
9.

Technology evaluation: cystic fibrosis therapy, Genzyme.

Cockett MI.

Curr Opin Mol Ther. 1999 Apr;1(2):279-83. Review.

PMID:
11715952
11.

Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice.

Ostrowski LE, Yin W, Diggs PS, Rogers TD, O'Neal WK, Grubb BR.

Gene Ther. 2007 Oct;14(20):1492-501. Epub 2007 Jul 19.

PMID:
17637798
12.

Adenovirus-mediated gene transfer to ciliated airway epithelia requires prolonged incubation time.

Zabner J, Zeiher BG, Friedman E, Welsh MJ.

J Virol. 1996 Oct;70(10):6994-7003.

13.

Sendai virus-mediated CFTR gene transfer to the airway epithelium.

Ferrari S, Griesenbach U, Iida A, Farley R, Wright AM, Zhu J, Munkonge FM, Smith SN, You J, Ban H, Inoue M, Chan M, Singh C, Verdon B, Argent BE, Wainwright B, Jeffery PK, Geddes DM, Porteous DJ, Hyde SC, Gray MA, Hasegawa M, Alton EW.

Gene Ther. 2007 Oct;14(19):1371-9. Epub 2007 Jun 28.

PMID:
17597790
14.

Single-dose lentiviral gene transfer for lifetime airway gene expression.

Stocker AG, Kremer KL, Koldej R, Miller DS, Anson DS, Parsons DW.

J Gene Med. 2009 Oct;11(10):861-7. doi: 10.1002/jgm.1368.

PMID:
19634193
15.

Inhibition by TNF-alpha and IL-4 of cationic lipid mediated gene transfer in cystic fibrosis tracheal gland cells.

Bastonero S, Gargouri M, Ortiou S, Guéant JL, Merten MD.

J Gene Med. 2005 Nov;7(11):1439-49.

PMID:
16001392
16.

A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis.

Knowles MR, Noone PG, Hohneker K, Johnson LG, Boucher RC, Efthimiou J, Crawford C, Brown R, Schwartzbach C, Pearlman R.

Hum Gene Ther. 1998 Jan 20;9(2):249-69.

PMID:
9472784
17.

The introduction of two silent mutations into a CFTR cDNA construct allows improved detection of exogenous mRNA in gene transfer experiments.

Hart SL, Mayall E, Stern M, Munkonge FM, Frost A, Huang L, Vasilliou M, Williamson R, Alton EW, Coutelle C.

Hum Mol Genet. 1995 Sep;4(9):1597-602.

PMID:
8541845
18.

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.

Caplen NJ, Alton EW, Middleton PG, Dorin JR, Stevenson BJ, Gao X, Durham SR, Jeffery PK, Hodson ME, Coutelle C, et al.

Nat Med. 1995 Jan;1(1):39-46. Erratum in: Nat Med 1995 Mar;1(3):272.

PMID:
7584951
19.

[Aerosol administration of a replication defective recombinant adenovirus expressing normal human cDNA-CFTR in the respiratory tractus in patients with cystic fibrosis].

Bellon G, Calmard L, Thouvenot D, Levrey H, Jagneaux V, Poitevin F, Malcus C, Accart N, Séné C, Layani MP, Aymard M, Bienvenu J, Courtney M, Döring G, Gilly B, Gilly R, Lamy D, Morel Y, Paulin C, Perraud F, Rodillon L, So S, Touraine F, Schatz C, Pavirani A.

C R Seances Soc Biol Fil. 1996;190(1):109-42. French.

PMID:
8881273
20.

Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

Flotte TR, Afione SA, Conrad C, McGrath SA, Solow R, Oka H, Zeitlin PL, Guggino WB, Carter BJ.

Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10613-7.

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