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Items: 1 to 20 of 122


Yeast DNA ligase IV mediates non-homologous DNA end joining.

Wilson TE, Grawunder U, Lieber MR.

Nature. 1997 Jul 31;388(6641):495-8.


Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes.

Chen L, Trujillo K, Ramos W, Sung P, Tomkinson AE.

Mol Cell. 2001 Nov;8(5):1105-15.


Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.

Chiruvella KK, Liang Z, Birkeland SR, Basrur V, Wilson TE.

PLoS Genet. 2013 Jun;9(6):e1003599. doi: 10.1371/journal.pgen.1003599. Epub 2013 Jun 27.


Recruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domain.

Palmbos PL, Wu D, Daley JM, Wilson TE.

Genetics. 2008 Dec;180(4):1809-19. doi: 10.1534/genetics.108.095539. Epub 2008 Oct 1.


Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.

Teo SH, Jackson SP.

Curr Biol. 2000 Feb 10;10(3):165-8.


Yeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining.

Chen X, Tomkinson AE.

J Biol Chem. 2011 Feb 11;286(6):4931-40. doi: 10.1074/jbc.M110.195024. Epub 2010 Dec 13.


Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination.

Zhang Y, Hefferin ML, Chen L, Shim EY, Tseng HM, Kwon Y, Sung P, Lee SE, Tomkinson AE.

Nat Struct Mol Biol. 2007 Jul;14(7):639-46. Epub 2007 Jun 24.


Role of the yeast DNA repair protein Nej1 in end processing during the repair of DNA double strand breaks by non-homologous end joining.

Yang H, Matsumoto Y, Trujillo KM, Lees-Miller SP, Osley MA, Tomkinson AE.

DNA Repair (Amst). 2015 Jul;31:1-10. doi: 10.1016/j.dnarep.2015.04.003. Epub 2015 Apr 21.


Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding.

Chiruvella KK, Renard BM, Birkeland SR, Sunder S, Liang Z, Wilson TE.

DNA Repair (Amst). 2014 Dec;24:37-45.


Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.

Wu D, Topper LM, Wilson TE.

Genetics. 2008 Mar;178(3):1237-49. doi: 10.1534/genetics.107.083535. Epub 2008 Feb 3.


Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

Manolis KG, Nimmo ER, Hartsuiker E, Carr AM, Jeggo PA, Allshire RC.

EMBO J. 2001 Jan 15;20(1-2):210-21.


Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae.

Milne GT, Jin S, Shannon KB, Weaver DT.

Mol Cell Biol. 1996 Aug;16(8):4189-98.


Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV.

Grob P, Zhang TT, Hannah R, Yang H, Hefferin ML, Tomkinson AE, Nogales E.

DNA Repair (Amst). 2012 Jan 2;11(1):74-81. doi: 10.1016/j.dnarep.2011.10.023. Epub 2011 Nov 15.


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