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Items: 1 to 20 of 268

1.

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner.

Fiscella M, Zhang H, Fan S, Sakaguchi K, Shen S, Mercer WE, Vande Woude GF, O'Connor PM, Appella E.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6048-53.

2.

Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia.

Khanna KK, Beamish H, Yan J, Hobson K, Williams R, Dunn I, Lavin MF.

Oncogene. 1995 Aug 17;11(4):609-18.

PMID:
7651723
4.

WAF1/p21 regulates proliferation, but does not mediate p53-dependent apoptosis in urothelial carcinoma cell lines.

Makri D, Schulz WA, Grimm M, Clasen S, Bojar H, Schmitz-Dräger BJ.

Int J Oncol. 1998 Mar;12(3):621-8.

PMID:
9472102
5.
6.

[Cell cycle regulation after exposure to ionizing radiation].

Teyssier F, Bay JO, Dionet C, Verrelle P.

Bull Cancer. 1999 Apr;86(4):345-57. Review. French.

7.

Diminished capacity for p53 in mediating a radiation-induced G1 arrest in established human tumor cell lines.

Li CY, Nagasawa H, Dahlberg WK, Little JB.

Oncogene. 1995 Nov 2;11(9):1885-92.

PMID:
7478618
8.

Wild-type p53 can induce p21 and apoptosis in neuroblastoma cells but the DNA damage-induced G1 checkpoint function is attenuated.

McKenzie PP, Guichard SM, Middlemas DS, Ashmun RA, Danks MK, Harris LC.

Clin Cancer Res. 1999 Dec;5(12):4199-207.

9.

The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation.

Li M, Zhou JY, Ge Y, Matherly LH, Wu GS.

J Biol Chem. 2003 Oct 17;278(42):41059-68. Epub 2003 Jul 29.

10.

Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells.

Lee SJ, Ha MJ, Lee J, Nguyen P, Choi YH, Pirnia F, Kang WK, Wang XF, Kim SJ, Trepel JB.

J Biol Chem. 1998 Apr 24;273(17):10618-23.

11.

p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.

Denko NC, Green SL, Edwards D, Giaccia AJ.

Exp Cell Res. 2000 Jul 10;258(1):82-91.

PMID:
10912790
12.

WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells.

Cuddihy AR, Jalali F, Coackley C, Bristow RG.

Mol Cancer Ther. 2008 Apr;7(4):980-92. doi: 10.1158/1535-7163.MCT-07-0471.

13.

UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner.

Haapajärvi T, Kivinen L, Heiskanen A, des Bordes C, Datto MB, Wang XF, Laiho M.

Exp Cell Res. 1999 Apr 10;248(1):272-9.

PMID:
10094833
15.

Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells.

Wu Q, Kirschmeier P, Hockenberry T, Yang TY, Brassard DL, Wang L, McClanahan T, Black S, Rizzi G, Musco ML, Mirza A, Liu S.

J Biol Chem. 2002 Sep 27;277(39):36329-37. Epub 2002 Jul 22.

16.

p53 modulates radiation sensitivity independent of p21 transcriptional activation.

Mazzatti DJ, Lee YJ, Helt CE, O'Reilly MA, Keng PC.

Am J Clin Oncol. 2005 Feb;28(1):43-50.

PMID:
15685034
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